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黎巴嫩贝鲁特自然绝经的年龄:生殖因素和生活方式因素的作用

Age at natural menopause in Beirut, Lebanon: the role of reproductive and lifestyle factors.

作者信息

Reynolds R F, Obermeyer C M

机构信息

Department of Population and International Health, Harvard University, Boston, Massachusetts 02115, USA.

出版信息

Ann Hum Biol. 2001 Jan-Feb;28(1):21-9. doi: 10.1080/03014460150201850.

Abstract

PRIMARY OBJECTIVE

To determine the median age of natural menopause and factors associated with the timing of menopause in Beirut, Lebanon. RESEARCH DESGIN: A population-based sample of 298 women were interviewed using a semi-structured questionnaire.

METHODS AND PROCEDURES

Logit analysis and logistic regression were used to estimate the median age and identify correlates of menopausal status.

MAIN OUTCOMES AND RESULTS

The median age of natural menopause in Beirut, Lebanon is estimated to be 49.3 years. Not being currently married (odds ratio (OR)=4.19, 95% CI: 1.53, 11.51) and smoking (OR = 1.02 for each year of smoking, 95% CI: 1.00, 1.05) are significantly associated with an earlier age at menopause. Women with menstrual bleeding longer than 5 days have later ages at menopause (OR = 0.50, 95% CI: 0.26, 0.97). Age at menarche, parity, education and socio-economic status are not statistically associated with the age at menopause.

CONCLUSIONS

The age at natural menopause in Lebanon is comparable to median ages reported for women in industrialized countries (49.3-51.4). Our results emphasize the role of smoking in determining an earlier age at menopause and indicate that reproductive characteristics affect the timing of menopause.

摘要

主要目标

确定黎巴嫩贝鲁特自然绝经的中位年龄以及与绝经时间相关的因素。研究设计:采用半结构化问卷对298名女性进行基于人群的抽样访谈。

方法与步骤

使用对数分析和逻辑回归来估计中位年龄并确定绝经状态的相关因素。

主要结果

黎巴嫩贝鲁特自然绝经的中位年龄估计为49.3岁。目前未婚(优势比(OR)=4.19,95%置信区间:1.53,11.51)和吸烟(每年吸烟的OR = 1.02,95%置信区间:1.00,1.05)与绝经年龄较早显著相关。月经出血超过5天的女性绝经年龄较晚(OR = 0.50,95%置信区间:0.26,0.97)。初潮年龄、产次、教育程度和社会经济地位与绝经年龄无统计学关联。

结论

黎巴嫩自然绝经年龄与工业化国家女性报告的中位年龄(49.3 - 51.4岁)相当。我们的结果强调了吸烟在确定较早绝经年龄方面的作用,并表明生殖特征会影响绝经时间。

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