Lakkis Najla A, Adib Salim M, Hamadeh Ghassan, El Jarrah Rana, Osman Mona H
Department of Family Medicine, American University of Beirut Medical Center (AUB-MC), Beirut, Lebanon. Email:
Asian Pac J Cancer Prev. 2017 May 1;18(5):1357-1364. doi: 10.22034/APJCP.2017.18.5.1357.
Background: Breast cancer is the leading cause of cancer death among females in Lebanon. This study aimed at analyzing its epidemiology in the country over time. Methods: Data were extracted from the Lebanese National Cancer Registry (NCR) for the years 2004 through 2010. Age-standardized and age-specific incidence rates for cancers per 100,000 population were calculated. Results: Breast cancer ranked first, accounting for an average of 37.6% of all new female cancer cases in Lebanon during the period of 2004-2010. Breast cancer was found to have been increasing faster than other hormone-related women’s cancers (i.e. of the ovaries and corpus uteri). The breast cancer age-standardized incidence rates (world population) (ASRw) increased steadily from 2004 (71.0) to 2010 (105.9), making the burden comparable to that in developed countries, reflecting the influence of sociological and reproductive patterns transitioning from regional norms to global trends. The age-specific incidence rates for breast cancer rose steeply from around age 35-39 years, to reach a first peak in the age group 45-49 years, and then dropped slightly between 50 and 64 years to rise again thereafter and reach a second peak in the 75+ age group. Five-year age-specific rates among Lebanese women between 35 and 49 years were among the highest observed worldwide in 2008. Conclusion: Breast cancer is continuously on the rise in Lebanon. The findings of this study support the national screening recommendation of starting breast cancer screening at the age of 40 years. It is mandatory to conduct an in-depth analysis of contributing factors and develop consequently a comprehensive National Breast Cancer Control strategy.
乳腺癌是黎巴嫩女性癌症死亡的主要原因。本研究旨在分析该国乳腺癌随时间变化的流行病学情况。方法：从黎巴嫩国家癌症登记处（NCR）提取2004年至2010年的数据。计算每10万人口中癌症的年龄标准化发病率和年龄别发病率。结果：乳腺癌位居榜首，在2004 - 2010年期间，平均占黎巴嫩所有新增女性癌症病例的37.6%。研究发现，乳腺癌的增长速度快于其他与激素相关的女性癌症（即卵巢癌和子宫体癌）。乳腺癌年龄标准化发病率（世界人口）（ASRw）从2004年的71.0稳步上升至2010年的105.9，这使得其负担与发达国家相当，反映了社会和生殖模式从地区规范向全球趋势转变的影响。乳腺癌的年龄别发病率从35 - 39岁左右开始急剧上升，在45 - 49岁年龄组达到第一个峰值，然后在50至64岁之间略有下降，此后再次上升，并在75岁及以上年龄组达到第二个峰值。2008年，黎巴嫩35至49岁女性的五年年龄别发病率是全球观察到的最高发病率之一。结论：黎巴嫩的乳腺癌发病率持续上升。本研究结果支持在40岁开始进行乳腺癌筛查的国家筛查建议。必须对促成因素进行深入分析，并据此制定全面的国家乳腺癌控制策略。
