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[恶性间皮瘤:45例有或无石棉暴露史患者的临床及影像学描述]

[Malignant mesothelioma: clinical and radiological description of 45 cases with and without asbestos exposure].

作者信息

García-López M P, Barrera-Rodríguez R

机构信息

Instituto Nacional de Enfermedades Respiratorias, Secretaría de Salud, México.

出版信息

Salud Publica Mex. 2000 Nov-Dec;42(6):511-9.

PMID:11201579
Abstract

OBJECTIVE

Our aim was to identify and describe the main symptoms, clinical presentation, and radiographic changes in malignant mesothelioma (MM) patients.

MATERIAL AND METHODS

We reviewed the medical and X-ray records of all patients diagnosed with MM, admitted between 1991 and 1998 to the National Institute of Respiratory Diseases (INER), which is a governmental institution specialized in chest disease in Mexico City. The following data were collected: Age, occupation, asbestos exposure, latency, family history of cancer, clinical symptoms, and X-ray changes. Data are presented as percentages by sex and age group.

RESULTS

We found 45 cases of MM; in 80% of them a history of asbestos exposure could not be documented. The 51-60 years age group had the highest frequency of MM. Dispnea and chest pain were the presenting symptoms in most patients. Pleural effusion and pleural thickening were the X-ray abnormalities observed in 75% of the patients.

CONCLUSIONS

The clinical and radiographic findings among patients with MM without asbestos exposure were similar to those with a history of asbestos exposure.

摘要

目的

我们的目的是识别并描述恶性间皮瘤(MM)患者的主要症状、临床表现及影像学改变。

材料与方法

我们回顾了1991年至1998年间收治于国家呼吸系统疾病研究所(INER)的所有确诊为MM患者的病历及X光记录,该研究所是墨西哥城一家专门诊治胸部疾病的政府机构。收集了以下数据:年龄、职业、石棉接触史、潜伏期、癌症家族史、临床症状及X光改变。数据按性别和年龄组以百分比形式呈现。

结果

我们发现45例MM患者;其中80%无法记录到石棉接触史。51 - 60岁年龄组MM发病率最高。大多数患者的首发症状为呼吸困难和胸痛。75%的患者X光检查异常表现为胸腔积液和胸膜增厚。

结论

无石棉接触史的MM患者的临床及影像学表现与有石棉接触史的患者相似。

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