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[恶性间皮瘤:45例有或无石棉暴露史患者的临床及影像学描述]

[Malignant mesothelioma: clinical and radiological description of 45 cases with and without asbestos exposure].

作者信息

García-López M P, Barrera-Rodríguez R

机构信息

Instituto Nacional de Enfermedades Respiratorias, Secretaría de Salud, México.

出版信息

Salud Publica Mex. 2000 Nov-Dec;42(6):511-9.

Abstract

OBJECTIVE

Our aim was to identify and describe the main symptoms, clinical presentation, and radiographic changes in malignant mesothelioma (MM) patients.

MATERIAL AND METHODS

We reviewed the medical and X-ray records of all patients diagnosed with MM, admitted between 1991 and 1998 to the National Institute of Respiratory Diseases (INER), which is a governmental institution specialized in chest disease in Mexico City. The following data were collected: Age, occupation, asbestos exposure, latency, family history of cancer, clinical symptoms, and X-ray changes. Data are presented as percentages by sex and age group.

RESULTS

We found 45 cases of MM; in 80% of them a history of asbestos exposure could not be documented. The 51-60 years age group had the highest frequency of MM. Dispnea and chest pain were the presenting symptoms in most patients. Pleural effusion and pleural thickening were the X-ray abnormalities observed in 75% of the patients.

CONCLUSIONS

The clinical and radiographic findings among patients with MM without asbestos exposure were similar to those with a history of asbestos exposure.

摘要

目的

我们的目的是识别并描述恶性间皮瘤(MM)患者的主要症状、临床表现及影像学改变。

材料与方法

我们回顾了1991年至1998年间收治于国家呼吸系统疾病研究所(INER)的所有确诊为MM患者的病历及X光记录,该研究所是墨西哥城一家专门诊治胸部疾病的政府机构。收集了以下数据:年龄、职业、石棉接触史、潜伏期、癌症家族史、临床症状及X光改变。数据按性别和年龄组以百分比形式呈现。

结果

我们发现45例MM患者;其中80%无法记录到石棉接触史。51 - 60岁年龄组MM发病率最高。大多数患者的首发症状为呼吸困难和胸痛。75%的患者X光检查异常表现为胸腔积液和胸膜增厚。

结论

无石棉接触史的MM患者的临床及影像学表现与有石棉接触史的患者相似。

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