Baris Y
IARC Sci Publ. 1980(30):937-47.
One hundred and eight-five cases of environmentally-caused malignant pleural mesothelioma were analysed for clinical and radiological pictures. The first group consisted of 122 subjects from villages with asbestos deposits. The second group consisted of 63 patients from the Cappadocia region where there are no asbestos deposits but where zeolite occurs. The mean age at death and the age range of the patients were lower than those of patients with occupationally-caused mesothelioma. This can be explained by the fact that exposure to mineral fibres in Turkey begins immediately after birth. The mode of onset was insidious chest pain, and the mean interval before reaching hospital was six months. The average duration of illness from the onset of symptoms to death was nearly 18 months. The most common clinical findings were evidence of pleural effusion and thickening. Bronchial breathing, tumour extension to the chest wall and frozen chest were also observed. Horner's syndrome was recorded in seven cases, and hypoglycaemia features in two. Pleural effusions and thickening, nodular and lobular lesions in the pleura, calcified pleural plaques with pleural lesions and hydropneumothorax were the radiological manifestations of malignant pleural mesothelioma. Three patients with mesothelioma were being followed up after a diagnosis of asbestos-caused pleurisy.
对185例环境因素导致的恶性胸膜间皮瘤患者的临床和影像学表现进行了分析。第一组由来自有石棉矿床村庄的122名受试者组成。第二组由来自卡帕多西亚地区的63名患者组成，该地区没有石棉矿床，但有沸石。患者的平均死亡年龄和年龄范围低于职业性间皮瘤患者。这可以用土耳其人出生后立即接触矿物纤维这一事实来解释。发病方式为隐匿性胸痛，入院前平均间隔时间为6个月。从症状出现到死亡的平均病程接近18个月。最常见的临床发现是胸腔积液和增厚的证据。还观察到支气管呼吸、肿瘤向胸壁扩展和胸廓固定。7例记录有霍纳综合征，2例有低血糖特征。胸腔积液和增厚、胸膜结节和小叶病变、伴有胸膜病变的钙化胸膜斑和气胸是恶性胸膜间皮瘤的影像学表现。3例间皮瘤患者在被诊断为石棉性胸膜炎后正在接受随访。
