Osman Elbek, Hasan Bayram, Meral Uyar, Ercan Akbulut, Mehmet Tülü, Nazan Bayram, Ayhan Ozkur, Erhan Ekinci, Oner Dikensoy
Department of Pulmonary Diseases, Gaziantep University, Gaziantep, Turkey.
Respirology. 2007 May;12(3):448-51. doi: 10.1111/j.1440-1843.2006.01027.x.
Environmental asbestos exposure is reportedly common in some districts of Turkey. The aim of this study was to investigate the presence and effect of environmental asbestos exposure in a village in Gaziantep, Turkey, with reported cases of mesothelioma.
All villagers > or =14 years old were subject to an interview rediagnosis and a detailed questionnaire. Chest microfilms were performed in all cases, and additional standard CXRs were obtained when necessary. Samples collected from the natural mantle, and whitewash from the houses were analysed for the presence of asbestos.
In total, 269 villagers took part in the study. The incidence of histopathologically diagnosed malignant pleural mesothelioma was 0.32% relative to the total village population in the year 2000. The verbal autopsy revealed eight possible cases of malignant pleural mesothelioma, all of whom had died within the past 12 years. Of these eight, there was a first-degree kinship between three, and additionally, these patients had a third-degree relationship with a biopsy proven case. Radiological evaluation showed pleural calcification and/or thickness in 3.3%, and pleural effusion in 0.4% of patients undergoing CXR. All houses in the village were constructed using adobe soil, and the interior whitewash was made from soil containing asbestos. Analysis of soil samples revealed tremolite and/or actinolyte asbestos.
The current findings suggest that environmental asbestos exposure continue to be a serious health concern in the Gaziantep region of Turkey.
据报道，在土耳其的一些地区，环境中石棉暴露情况较为常见。本研究旨在调查土耳其加济安泰普省一个村庄的环境石棉暴露情况及其影响，该村庄有间皮瘤病例报告。
所有14岁及以上的村民均接受访谈重新诊断及详细问卷调查。所有病例均拍摄胸部微片，必要时拍摄额外的标准胸部X光片。对取自天然地幔的样本以及房屋粉刷层进行石棉检测。
共有269名村民参与了本研究。2000年，经组织病理学诊断的恶性胸膜间皮瘤发病率相对于全村总人口为0.32%。口头尸检发现8例可能的恶性胸膜间皮瘤病例，均在过去12年内死亡。其中8例中，3例有一级亲属关系，此外，这些患者与1例活检确诊病例有三级亲属关系。放射学评估显示，接受胸部X光检查的患者中，3.3%有胸膜钙化和/或增厚，0.4%有胸腔积液。该村庄所有房屋均使用土坯建造，内部粉刷层由含石棉的土壤制成。土壤样本分析发现透闪石和/或阳起石石棉。
目前的研究结果表明，在土耳其加济安泰普地区，环境石棉暴露仍是一个严重的健康问题。
