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双嘧达莫铊闪烁扫描术和多巴酚丁胺负荷超声心动图作为腹主动脉重建术后心脏并发症预测指标的价值。

The value of dipyridamole thallium scintigraphy and dobutamine stress echocardiography as predictors of cardiac complications following reconstruction of the abdominal aorta.

作者信息

Lacroix H, Herregod M C, Ector H, Vandeplas A, Nevelsteen A, Suy R

机构信息

Department of Vascular Surgery, University Hospital, Leuven, Belgium.

出版信息

Int Angiol. 2000 Sep;19(3):231-6.

Abstract

BACKGROUND

The aim of this study was to evaluate the ability of dipyridamole thallium scintigraphy and dobutamine stress echocardiography to predict cardiac complications following elective reconstruction of the abdominal aorta in patients with a stable preoperative cardiac condition and to compare this with information obtained from the medical history, ECG and resting echocardiography alone.

METHODS

This evaluation was performed from January 1993 until December 1995 as part of a prospective, randomised study in 200 patients, with a mean age of 65 (5% women). Dipyridamole thallium scintigraphy was performed on 195 patients and dobutamine stress echocardiography was added to the protocol in the last 83 patients. Cardiac complications were defined before the start of the study.

RESULTS

In the postoperative period 62 cardiac complications occurred (31%). In patients clinically suspected of having coronary artery disease the incidence of complications was 40% (51/126), compared to 15% (11/74) when no coronary pathology was suspected (p<0.001). When reversible defects were present on dipyridamole thallium scintigraphy the incidence of complications was 36% (20/55), compared to 29% (41/140) when no reversible defects had been found (NS). Dobutamine stress echocardiography was impossible or contraindicated in 21 patients. In the remaining patients the incidence of complications was 71% (5/7) when new regional wall motion abnormalities were found, compared to 16% (9/55) when such abnormalities had not been detected (p<0.005).

CONCLUSIONS

These data suggest that cardiac complications following reconstruction of the abdominal aorta in patients with a stable cardiac condition are best predicted by dobutamine stress echocardiography. Dipyridamole thallium scintigraphy, however, does not seem to be useful in this respect.

摘要

背景

本研究旨在评估双嘧达莫铊闪烁扫描术和多巴酚丁胺负荷超声心动图预测术前心脏状况稳定的患者择期腹主动脉重建术后心脏并发症的能力,并将其与仅从病史、心电图和静息超声心动图获得的信息进行比较。

方法

作为一项前瞻性随机研究的一部分,于1993年1月至1995年12月对200例患者进行了评估,患者平均年龄65岁(5%为女性)。195例患者接受了双嘧达莫铊闪烁扫描术,最后83例患者的方案中增加了多巴酚丁胺负荷超声心动图。在研究开始前对心脏并发症进行了定义。

结果

术后发生62例心脏并发症(31%)。临床怀疑患有冠状动脉疾病的患者并发症发生率为40%(51/126),而未怀疑有冠状动脉病变的患者并发症发生率为15%(11/74)(p<0.001)。双嘧达莫铊闪烁扫描术出现可逆性缺损时并发症发生率为36%(20/55),未发现可逆性缺损时并发症发生率为29%(41/140)(无显著性差异)。21例患者无法进行或禁忌进行多巴酚丁胺负荷超声心动图检查。在其余患者中,发现新的节段性室壁运动异常时并发症发生率为71%(5/7),未检测到此类异常时并发症发生率为16%(9/55)(p<0.005)。

结论

这些数据表明,多巴酚丁胺负荷超声心动图最能预测心脏状况稳定的患者腹主动脉重建术后的心脏并发症。然而,双嘧达莫铊闪烁扫描术在这方面似乎并无用处。

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