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大动脉炎的颈动脉重建:全自体静脉移植策略的必要性及一种新手术的开展

Carotid artery reconstruction for Takayasu's arteritis the necessity of all-autogenous-vein graft policy and development of a new operation.

作者信息

Tada Y, Kamiya K, Shindo S, Miyata T, Koyama H, Sato O, Ariizumi K

机构信息

Second Department of Surgery, Yamanashi Medical University, Japan.

出版信息

Int Angiol. 2000 Sep;19(3):242-9.

Abstract

BACKGROUND

We have adopted an all-autogenous-vein-graft policy in carotid reconstruction for Takayasu arteritis, namely an ascendo-right carotid and right subclavian (axillary) arteries bypass using a pantaloon vein graft for patients all of whose arch branches are occluded, and an extra-anatomical bypass from the right subclavian artery for patients whose brachiocephalic artery is the only arch branch that remains patent. This report is to elaborate on these operations and to assess the long-term outcome.

METHODS

Six patients were operated on according to this policy; (5 women, 1 man, age range: 14 to 59 years (mean: 30). The indications for surgery were severe cerebral ischaemia that significantly interfered with their daily lives. The pantaloon vein graft bypass was performed in four patients, and an extra-anatomical bypass in two. The specific management protocol to prevent the "postbypass hyperperfusion syndrome" and cerebral oedema included a shunt procedure to the internal carotid artery using one limb of the pantaloon vein graft, induced hypotension just before the completion of the carotid reconstruction and the administration of a glycerine-fructose solution.

RESULTS

Cerebral ischaemic symptoms disappeared in all patients. All but one, who died of a ruptured thoraco-abdominal aneurysm on the 35th postoperative month, are living a normal life with a patent graft. No suture line complications have as yet been encountered (follow-up: 10 to 205 months, mean: 126 months).

CONCLUSIONS

Carotid vein bypass for Takayasu arteritis, particularly, the pantaloon vein graft bypass is recommended for those of whom all aortic arch branches are occluded, resulting in severe brain ischaemia. Perioperative blood pressure control is important for prevention of the hyperperfusion syndrome.

摘要

背景

我们在大动脉炎颈动脉重建中采用了全自体静脉移植策略,即对于所有主动脉弓分支均闭塞的患者,使用裤型静脉移植进行升主动脉 - 右颈动脉和右锁骨下(腋)动脉搭桥;对于仅头臂动脉仍保持通畅的主动脉弓分支患者,进行从右锁骨下动脉的解剖外搭桥。本报告旨在详细阐述这些手术并评估长期疗效。

方法

根据该策略对6例患者进行了手术(5例女性,1例男性,年龄范围:14至59岁,平均30岁)。手术指征为严重脑缺血,严重影响其日常生活。4例患者进行了裤型静脉移植搭桥,2例进行了解剖外搭桥。预防“搭桥后高灌注综合征”和脑水肿的具体管理方案包括使用裤型静脉移植的一个分支进行颈内动脉分流术、在颈动脉重建完成前诱导低血压以及给予甘油果糖溶液。

结果

所有患者的脑缺血症状均消失。除1例在术后第35个月死于胸腹主动脉瘤破裂外,其余患者均凭借通畅的移植血管正常生活。尚未遇到缝合线并发症(随访:10至205个月,平均126个月)。

结论

大动脉炎的颈动脉静脉搭桥,特别是对于所有主动脉弓分支均闭塞、导致严重脑缺血的患者,推荐使用裤型静脉移植搭桥。围手术期血压控制对于预防高灌注综合征很重要。

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