Saitoh E, Adachi-Usami E, Mizota A, Fujimoto N
Department of Ophthalmology, Chiba University School of Medicine, Japan.
J Pediatr Ophthalmol Strabismus. 2001 Jan-Feb;38(1):21-6. doi: 10.3928/0191-3913-20010101-08.
To verify the efficiency and objectivity of the pattern visual evoked potential (VEP) for organic disorders of the cortical visual system.
This retrospective study evaluated VEP in 19 patients diagnosed with psychogenic visual disturbance, 7 patients with malingering, and 37 age-matched normal volunteers. Transient (3 reversals per second) and steady-state (12 reversals per second) pattern VEPs for check sizes 15' and 30', with a contrast of 80%, were recorded.
The amplitudes of both transient and steady-state pattern VEPs were significantly increased in patients with psychogenic visual disturbance, while patients with malingering had significantly lower amplitudes. P100 peak latency was prolonged in both groups of patients.
Monitoring of patients' fixation on the stimulus showed those with psychogenic visual disturbance fixated well on the stimulus, while those with malingering did not. This finding produced a VEP amplitude reduction in patients with malingering. The reason for the VEP amplitude in patients with psychogenic visual disturbance is unclear.
验证图形视觉诱发电位（VEP）对皮质视觉系统器质性疾病诊断的有效性和客观性。
本回顾性研究评估了19例诊断为精神性视觉障碍的患者、7例诈病患者以及37名年龄匹配的正常志愿者的VEP。记录了15'和30'视标、对比度为80%的瞬态（每秒3次反转）和稳态（每秒12次反转）图形VEP。
精神性视觉障碍患者的瞬态和稳态图形VEP波幅均显著增加，而诈病患者的波幅显著降低。两组患者的P100峰潜伏期均延长。
对患者注视刺激情况的监测显示，精神性视觉障碍患者能很好地注视刺激，而诈病患者则不能。这一发现导致诈病患者的VEP波幅降低。精神性视觉障碍患者VEP波幅增加的原因尚不清楚。
