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[布达佩斯儿童哮喘患病率的上升与空气污染数据及总花粉计数的关系]

[Increase in prevalence of childhood asthma in Budapest in relation to the air pollution data and the total pollen count].

作者信息

Endre L, Vámos A, Dinya E, Farkas I

机构信息

Központi MAV Kórház-Rendelóintézet, Budapest.

出版信息

Orv Hetil. 2000 Dec 24;141(52):2815-20.

Abstract

The authors surveyed the prevalence of bronchial asthma in childhood in Budapest in 1995 and in February 1999, via questionnaires directed to paediatricians. In 1995, replies were received from 118 paediatricians in 11 districts, who were responsible for the supervision of 104,087 children, of these, 1.88 +/- 0.87% had been diagnosed as having asthma. In 1999, replies were sent by 153 physicians in 22 of the 23 districts, who had a total of 142,684 children under their care. These included 3228 asthmatics, i.e. a prevalence of 2.26 +/- 0.95%. The difference between the two data was highly significant (p = 0.0001). The prevalence increased by 20% in 4 years. The dust, CO, NO2 and SO2 concentrations in the air were measured constantly at 8 points in Budapest, while ozone level measurements were also made at 2 stations. The counts of pollens and of fungal elements in the air were calculated separately for Buda and for Pest. These data overall revealed that the level of air pollution in Budapest did not deteriorate in the period in question, and the pollen counts from allergizing plants did not rise relative to earlier years. An interesting question (though it is far from certain that this is a causal correlation) can be upposed whether the 13% drop in the number of live births in Hungary during this 4-year period can be connected with the 20% rise in prevalence of childhood asthma.

摘要

作者于1995年及1999年2月,通过向儿科医生发放问卷的方式,对布达佩斯儿童支气管哮喘的患病率进行了调查。1995年,收到了来自11个区的118名儿科医生的回复,他们负责监管104,087名儿童,其中1.88±0.87%被诊断患有哮喘。1999年,23个区中的22个区的153名医生进行了回复,他们共照料142,684名儿童。其中有3228名哮喘患者,即患病率为2.26±0.95%。这两个数据之间的差异具有高度显著性(p = 0.0001)。患病率在4年中上升了20%。在布达佩斯的8个点持续测量了空气中的灰尘、一氧化碳、二氧化氮和二氧化硫浓度,同时还在2个站点进行了臭氧水平测量。分别计算了布达和佩斯空气中花粉和真菌成分的数量。这些数据总体显示,在所述期间布达佩斯的空气污染水平没有恶化,致敏植物的花粉数量相对于前几年也没有增加。一个有趣的问题(尽管远不能确定这是一种因果关系)是,在这4年期间匈牙利活产数下降13%是否与儿童哮喘患病率上升20%有关。

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