Gurer G, Saygi S, Ciger A
Hacettepe University, Ankara, Turkey.
Clin Electroencephalogr. 2001 Jan;32(1):1-9. doi: 10.1177/155005940103200103.
In this study we reviewed the clinical, electrophysiological and neuroimaging data of 21 patients with epilepsia partialis continua (EPC), which is a rare form of epilepsy with focal motor seizures persisting hours to years. We found infections, cerebrovascular events and tumors as the most common causes of EPC in adults. SSPE was also shown as a cause of EPC. EPC in SSPE patients was resistant to therapies and persisted more than 1 year. EPC is usually a predictor of poor outcome and 29% of patients died after EPC in this study. As prognosis is usually bad and as response to treatment is poor in patients who had EPC, early diagnosis and treatment of the underlying cause is important. Although the most common etiologies are infections, cerebrovascular events and tumors, if EPC persists several months SSPE should be kept in mind as a rare cause of EPC. MRI should be repeated in chronic cases to show dysplastic cortex, which was shown in 1 patient in this study.
在本研究中，我们回顾了21例持续性部分性癫痫（EPC）患者的临床、电生理和神经影像学数据，EPC是一种罕见的癫痫形式，其局灶性运动性癫痫发作可持续数小时至数年。我们发现感染、脑血管事件和肿瘤是成人EPC最常见的病因。亚急性硬化性全脑炎（SSPE）也被证明是EPC的病因之一。SSPE患者的EPC对治疗有抵抗性且持续超过1年。EPC通常是预后不良的一个指标，在本研究中，29%的患者在发生EPC后死亡。由于预后通常较差，且EPC患者对治疗的反应不佳，因此对潜在病因进行早期诊断和治疗很重要。虽然最常见的病因是感染、脑血管事件和肿瘤，但如果EPC持续数月，应将SSPE作为EPC的一种罕见病因加以考虑。对于慢性病例，应重复进行磁共振成像（MRI）检查以显示发育异常的皮质，本研究中有1例患者显示出这种情况。
