Dissolution behavior of hydroxyapatite coating by hydrothermal method: an in vitro study.

Hydroxyapatite (HA) coated CaO-SiO2-B2O3-Na2O glass composites prepared by a hydrothermal coating method were soaked in four kinds of solutions to evaluate the dissolution behavior and the chemical stability. 0.5 mol/l HCl and 0.5 mol/l HNO3 were used as acidic solution, and 5% physiological saline and sodium lactate compound solution as the neutral physiological solution. It was found that HA coated glass composites had the better chemical stability and the corroding-resistance ability. The dissolution behavior of the HA coating was mainly correlated with the phase composition of the as-received HA coating and its microstructure as well as the pH value of the solution.