1α-羟胆钙化醇：一种治疗肾性骨病的方法。
I alpha-hydroxycholecalciferol: a treatment of renal bone disease.
作者信息
Catto G R, MacLeod M, Pelc B, Kodicek E
出版信息
Br Med J. 1975 Jan 4;1(5948):12-4. doi: 10.1136/bmj.1.5948.12-a.
Abstract
Three patients with chronic renal failure on maintenance haemodialysis have been treated with 1 alpha-hydroxycholecalciferol (1 alpha-OHCC), a synthetic vitamin D analogue. A daily dose of 2 mug by mouth produced a significant increase in both calcium absorption from the gastrointestinal tract and calcium content of bone. Treatment with 1 alpha-OHCC appears to be effective in cases of metabolic bone disease associated with chronic renal failure.
摘要
三名维持性血液透析的慢性肾衰竭患者接受了合成维生素D类似物1α-羟胆钙化醇（1α-OHCC）的治疗。每日口服2微克该药物可使胃肠道对钙的吸收及骨钙含量显著增加。对于与慢性肾衰竭相关的代谢性骨病，1α-OHCC治疗似乎有效。
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