Gajdatsy A D, Kosmin A, Barrett G D
Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Clin Exp Ophthalmol. 2000 Dec;28(6):434-6. doi: 10.1046/j.1442-9071.2000.00352.x.
A 17-year-old youth presented with bilateral follicular conjunctivitis and nummular subepithelial corneal infiltrates. Failure of this to settle in an outpatient setting led to corneal scraping with microscopy and culturing for bacteria, fungi, Herpes simplex, adenovirus and Acanthamoeba as an inpatient. Polymerase chain reaction analysis of corneal cells was positive for adenovirus, and culture on live Escherichia coli-coated agar plates was positive for Acanthamoeba by phase contrast microscopy on day two. We conclude that Acanthomoeba infection can complicate adenoviral keratoconjunctivitis. This observation is in keeping with previously reported modes of infection by Acanthamoeba, whereby any epithelial breach seems to allow inoculation of the eye by this opportunistic organism.
一名17岁青年出现双侧滤泡性结膜炎和钱币状上皮下角膜浸润。在门诊治疗未能缓解，遂住院进行角膜刮片检查，镜检并培养细菌、真菌、单纯疱疹病毒、腺病毒和棘阿米巴。角膜细胞的聚合酶链反应分析显示腺病毒呈阳性，在涂有活大肠杆菌的琼脂平板上培养，第二天通过相差显微镜检查发现棘阿米巴呈阳性。我们得出结论，棘阿米巴感染可使腺病毒性角结膜炎复杂化。这一观察结果与先前报道的棘阿米巴感染模式一致，即任何上皮破损似乎都能让这种机会性生物体接种到眼睛中。
