Kaplenko O V, Korkhov V V, Lesik E A
Laboratory of Pharmacology, Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, Mendeleevskaya Liniya 3, St. Petersburg, 199034 Russia.
Eksp Klin Farmakol. 2000 Nov-Dec;63(6):28-9.
Verapamil and gynipral administered to pregnant rats in doses on a clinical level suppress the uterine contractions, which is manifested by a decrease in the amplitude and frequency of the biopotential. The joint administration of gynipral and verapamil (in half doses) resulted in a pronounced tocolytic effect.
以临床剂量给予怀孕大鼠维拉帕米和绞股蓝总苷可抑制子宫收缩，这表现为生物电位的幅度和频率降低。绞股蓝总苷和维拉帕米联合给药（半剂量）产生了显著的宫缩抑制作用。
