Korkhov V V, Mengal E V, Lesik E A, Petrosian M A
Laboratory of Pharmacology, Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg, Russia.
Eksp Klin Farmakol. 2000 Jul-Aug;63(4):32-4.
The effect of instenon upon the uterine contractile activity was studied in pregnant rats. The drug administration at a dose resulted in significant suppression of the myometrium contractility. The effect was not decreased when instenon was injected against the background of oxytocin. On the other hand, the concurrent injection of oxytocin upon a single or long-term administration of instenon produced a pronounced stimulating action on the myometrium contractility.
在妊娠大鼠中研究了因斯通（instenon）对子宫收缩活动的影响。以一定剂量给药该药物导致子宫肌层收缩力显著受到抑制。当在催产素背景下注射因斯通时，这种作用并未减弱。另一方面，在单次或长期给予因斯通的同时注射催产素，对子宫肌层收缩力产生了明显的刺激作用。
