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白塞病动脉受累的再次手术结果。

Reoperation results of arterial involvement in Behçet's disease.

作者信息

Ozeren M, Mavioglu I, Dogan O V, Yucel E

机构信息

Department of Cardiovascular Surgery, SSK Ankara Training Hospital, Turkey.

出版信息

Eur J Vasc Endovasc Surg. 2000 Dec;20(6):512-9. doi: 10.1053/ejvs.2000.1240.

Abstract

OBJECTIVES

to retrospectively evaluate the role of vascular interventions in Behçet's disease with arterial involvement. So far, little information is available on the surgical approach for arterial involvement in Behçet's disease.

MATERIAL AND METHODS

between February 1989 and August 1997, among 178 patients with Behçet's disease referred to our clinic, vascular involvement was established in total of 67 patients (38%) which consisted of 59 venous (33%) and 12 (7%) arterial involvements requiring urgent surgical intervention. Primary arterial lesions were occlusive in one patient, aneurysm formation in nine or both in four.

RESULTS

twelve primary operations and 12 reoperations were performed. The reasons for reoperations were anastomotic aneurysms, graft occlusion, occlusion of native vessel, graft infection, bleeding from anastomosis and aortoenteric fistula. First reoperation was performed after a mean period of 6.4 months (1-15 months). Postoperative follow-up was 12-60 months (mean 36 months) and three patients died during follow-up.

CONCLUSIONS

the surgical results were not satisfactory because of progressive graft thrombosis and formation of new aneurysms at the anastomosis. Aggressive medical treatment should be combined when major vessel involvement occurs. All types of arterial punctures for angiography or blood gases should be minimised because of the risk of new aneurysm formation. Surgical intervention is indicated only in patients with a growing aneurysm, acute rupture or severe ischaemia.

摘要

目的

回顾性评估血管介入治疗在伴有动脉受累的白塞病中的作用。到目前为止,关于白塞病动脉受累的手术治疗方法的信息很少。

材料与方法

1989年2月至1997年8月期间,在转诊至我院门诊的178例白塞病患者中,共有67例(38%)出现血管受累,其中59例(33%)为静脉受累,12例(7%)为动脉受累,需要紧急手术干预。原发性动脉病变中,1例为闭塞性病变,9例为动脉瘤形成,4例为两者皆有。

结果

共进行了12例初次手术和12例再次手术。再次手术的原因包括吻合口动脉瘤、移植物闭塞、自身血管闭塞、移植物感染、吻合口出血和主动脉肠瘘。首次再次手术平均在6.4个月(1 - 15个月)后进行。术后随访时间为12 - 60个月(平均36个月),随访期间有3例患者死亡。

结论

由于移植物血栓形成进展以及吻合口处新动脉瘤的形成,手术效果并不理想。当出现大血管受累时,应联合积极的药物治疗。由于存在形成新动脉瘤的风险,应尽量减少用于血管造影或血气分析的各种动脉穿刺。仅在动脉瘤增大、急性破裂或严重缺血的患者中才考虑手术干预。

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