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白塞病致巨大冠状动脉瘤伴晕厥发作 1 例报告

Giant coronary aneurysm of Behcet's disease with sudden syncope: a case report.

机构信息

Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, PR China.

Department of Cardiac Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

BMC Cardiovasc Disord. 2023 Sep 15;23(1):463. doi: 10.1186/s12872-023-03501-7.

DOI:10.1186/s12872-023-03501-7
PMID:37715142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10503119/
Abstract

Behcet's disease(BD) is a chronic inflammatory vasculitis that rarely affects the arteries, making myocardial infarction unlikely. We report a 28-year-old patient who was admitted to our hospital with multiple sudden syncope. Cardiovascular risk factors such as hypertension (HT), diabetes and obesity were not found in her. Preoperatively, imaging examinations suggested thrombosis of the inferior and superior vena cava and right heart combined with coronary artery aneurysm. The patient was finally diagnosed with a huge coronary artery aneurysm proximal to the left anterior descending artery. Syncope is considered to be caused right ventricular outflow tract obstruction. The patient received a successful aneurysm resection and had an uneventful postoperative recovery.

摘要

白塞病(BD)是一种慢性炎症性脉管炎,很少累及动脉,因此心肌梗死不太可能发生。我们报告了一例 28 岁女性患者,因多次突发晕厥而入院。她没有高血压(HT)、糖尿病和肥胖等心血管危险因素。术前影像学检查提示下腔静脉和上腔静脉及右心血栓形成,并合并冠状动脉瘤。最终诊断为左前降支近端巨大冠状动脉瘤。晕厥被认为是由右心室流出道梗阻引起的。患者成功地进行了动脉瘤切除术,术后恢复顺利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/10503119/22d120f2f026/12872_2023_3501_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/10503119/6cdd5bb4d5f0/12872_2023_3501_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/10503119/22d120f2f026/12872_2023_3501_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/10503119/6cdd5bb4d5f0/12872_2023_3501_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/10503119/22d120f2f026/12872_2023_3501_Fig2_HTML.jpg

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本文引用的文献

1
A Contemporary Review of Behcet's Syndrome.《贝赫切特综合征的当代综述》。
Clin Rev Allergy Immunol. 2021 Dec;61(3):363-376. doi: 10.1007/s12016-021-08864-3. Epub 2021 Jun 2.
2
A giant aneurysm of the left anterior descending coronary artery in the setting of Behcet's disease.白塞病背景下左前降支冠状动脉巨大动脉瘤。
Cardiovasc J Afr. 2020 Jan/Feb;31(1):e1-e3. doi: 10.5830/CVJA-2019-031.
3
Behçet syndrome: a contemporary view.白塞综合征:现代观点。
Nat Rev Rheumatol. 2018 Feb;14(2):107-119. doi: 10.1038/nrrheum.2017.208. Epub 2018 Jan 3.
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Acute coronary syndrome in Behcet's disease caused by a coronary artery aneurysm and thrombosis.白塞病中由冠状动脉瘤和血栓形成引起的急性冠状动脉综合征。
Eur J Rheumatol. 2014 Dec;1(4):156-158. doi: 10.5152/eurjrheumatol.2014.140042. Epub 2014 Dec 1.
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Cardiac findings in patients with Behçet's disease: Facts and controversies.白塞病患者的心脏表现:事实与争议
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Resolution of intracardiac and pulmonary thrombi without anticoagulation in a patient with Behçet's disease: a case report.Behçet 病患者心内和肺内血栓不经抗凝治疗而溶解:病例报告。
Clin Exp Rheumatol. 2013 May-Jun;31(3 Suppl 77):90-2. Epub 2013 Mar 4.
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Major vascular involvement in Behçet's disease: a retrospective study of 796 patients.白塞病的主要血管受累:796 例回顾性研究。
Clin Rheumatol. 2013 Jun;32(6):845-52. doi: 10.1007/s10067-013-2205-7. Epub 2013 Feb 27.
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Management and prognosis of nonpulmonary large arterial disease in patients with Behçet disease.Behçet 病患者非肺部大血管疾病的管理和预后。
J Vasc Surg. 2012 Jan;55(1):157-63. doi: 10.1016/j.jvs.2011.07.049. Epub 2011 Sep 23.
9
Cardiac and great vessel involvement in "Behcet's disease".白塞病中心脏及大血管受累情况
J Card Surg. 2008 Nov-Dec;23(6):765-8. doi: 10.1111/j.1540-8191.2008.00607.x.
10
Pulmonary and cardiac involvement in Behçet disease: 3 case reports.白塞病的肺部和心脏受累:3例病例报告。
Clin Appl Thromb Hemost. 2007 Jul;13(3):318-22. doi: 10.1177/1076029607302437.