Bensaid Y, Ameur A, Kabiri H, Mekouar T, Mesnaoui A, Ammar F, Benyahia B
Clinique chirurgicale D, CHU Avicenne, Rabat, Maroc.
J Mal Vasc. 1997 Mar;22(1):24-8.
Vascular involvement, usually venous thrombosis, is common in Behçet's disease. Arterial manifestations, usually aneurysms or more rarely occlusion, are less common. We analyzed 13 cases of Behçet's disease with arterial complications. This fourth series in the literature was collected over 11 years. There were 12 men and 1 woman, mean age 41 +/- 7 years. Mean delay to arterial complications was 5.8 years (maximum 20 years) after the first sign of the disease. In the 13 patients in our series, there were a total of 18 arterial lesions, including one aneurysm and one stenosis of the internal carotid artery. There were 2 cases (10%) with lesions of the aorta (aneurysms). Approximately half of the arterial lesions (7/18) involved the femoral artery. There were 11 localizations on the femoropopliteal axis (11 aneurysms). One aneurysm of the humeral artery was the only localization in the upper limb. Vascular involvement was limited to arterial lesions in 9/13 patients with multiple lesions at different localizations in 2 patients. In two others, a second arterial localization occurred secondarily. All patients except one were operated. Mid-term complications are: 1 death and 4 thrombi including 3 with good results after reoperation. In these patients with Behçet's disease, risk of severe complications is important, requiring long-term surveillance.
血管受累,通常为静脉血栓形成,在白塞病中很常见。动脉表现,通常为动脉瘤,或更罕见的闭塞,较为少见。我们分析了13例伴有动脉并发症的白塞病病例。该文献中的第四个系列是在11年期间收集的。有12名男性和1名女性,平均年龄41±7岁。从疾病的首个症状出现到发生动脉并发症的平均延迟时间为5.8年(最长20年)。在我们系列中的13例患者中,共有18处动脉病变,包括1例动脉瘤和1例颈内动脉狭窄。有2例(10%)出现主动脉病变(动脉瘤)。大约一半的动脉病变(7/18)累及股动脉。在股腘动脉轴线上有11处病变(11例动脉瘤)。1例肱动脉动脉瘤是上肢唯一的病变部位。在13例患者中,9例患者的血管受累仅限于动脉病变,2例患者在不同部位有多处病变。在另外两例中,继发出现了第二个动脉病变部位。除1例患者外,所有患者均接受了手术。中期并发症包括:1例死亡和4例血栓形成,其中3例在再次手术后效果良好。在这些白塞病患者中,严重并发症的风险很大,需要长期监测。