Harting J K, Updyke B V, Van Lieshout D P
Department of Anatomy, University of Wisconsin, Madison 53706, USA.
Exp Brain Res. 2001 Jan;136(1):138-42. doi: 10.1007/s002210000606.
The visual-recipient sector of the cat striatum receives corticostriate input from over 15 higher visual and oculomotor-related areas of the cortex and appears homologous with the physiologically characterized region of mixed visual and oculomotor inputs within the primate caudate nucleus. This area in the cat involves the dorsolateral caudate and a strip of the caudal putamen. In a first series of experiments, the former was injected with a retrograde tracer in several cats. Thalamostriate cells were found in extensive regions, including the intralaminar nuclei, certain motor-related nuclei, and, most notably, across much of the extrageniculate visual thalamus. In another set of experiments, anterograde tracers were also injected into the superior colliculus (SC), and labeled tectothalamic fibers were observed in all thalamic sites projecting to the visual-recipient striatum. These findings highlight for the first time the need for the SC to be considered in models of thalamostriate and visual/oculomotor-striatal function(s). Moreover, the data bring to light the fact that basal-ganglia outflow reaching the SC via striatonigro-nigrotectal circuitry is well positioned to modulate ascending tecto-thalamic-thalamostriatal signals destined for the visual-recipient striatum.
猫纹状体的视觉接收区从超过15个与视觉和眼球运动相关的高级皮质区域接收皮质纹状体输入，并且似乎与灵长类动物尾状核内具有生理特征的混合视觉和眼球运动输入区域同源。猫的这个区域包括背外侧尾状核和尾侧壳核的一条带。在第一组实验中，在几只猫中向背外侧尾状核注射了逆行示踪剂。在广泛区域发现了丘脑纹状体细胞，包括板内核、某些与运动相关的核，最显著的是，在大部分外侧膝状体以外的视觉丘脑中都有发现。在另一组实验中，还将顺行示踪剂注射到上丘（SC），并且在所有投射到视觉接收纹状体的丘脑部位都观察到了标记的顶盖丘脑纤维。这些发现首次凸显了在丘脑纹状体和视觉/眼球运动-纹状体功能模型中考虑上丘的必要性。此外，数据揭示了这样一个事实，即通过纹状体黑质-黑质顶盖回路到达上丘的基底神经节输出，能够很好地调节发往视觉接收纹状体的上行顶盖-丘脑-丘脑纹状体信号。
