一些新型4-羟基-2H-1,4-苯并恶嗪-3(4H)-酮的合成及其抗菌活性
Synthesis and antimicrobial activity of some new 4-hydroxy-2H- 1,4-benzoxazin-3(4H)-ones.
作者信息
Ozden S, Oztürk A M, Göker H, Altanlar N
机构信息
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan, Turkey.
出版信息
Farmaco. 2000 Nov-Dec;55(11-12):715-8. doi: 10.1016/s0014-827x(00)00098-7.
Abstract
Some 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Compounds 9, and 10 exhibited the best activity against Candida albicans.
摘要
合成了一些4-羟基-2H-1,4-苯并恶嗪-3(4H)-酮，并对它们针对金黄色葡萄球菌、大肠杆菌和白色念珠菌的抗菌活性进行了评估。化合物9和10对白色念珠菌表现出最佳活性。
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