Gowda R M, Khan I A, Sacchi T J, Vasavada B C
Department of Medicine, Long Island College Hospital, Brooklyn, NY, USA.
Angiology. 2001 Jan;52(1):59-62. doi: 10.1177/000331970105200108.
Scleroderma pericardial disease is usually silent and benign. The incidence of pericardial involvement in scleroderma is about 50% according to autopsy results, but symptomatic pericarditis manifests in about 16% of patients with diffuse scleroderma and in about 30% of patients with limited scleroderma. The clinically evident pericardial effusion is rare in scleroderma, although it can be detected in about 41% of patients with echocardiography. In majority of the patients, the pericardial effusion is small and not associated with symptoms. The pericardial effusion manifests usually after the manifestation of the other clinical and serologic features of scleroderma. A case of scleroderma is reported that presented with a large pericardial effusion, which antedated the other clinical and serologic features of scleroderma. The pericardial involvement in scleroderma is reviewed.
硬皮病心包疾病通常无明显症状且为良性。根据尸检结果，硬皮病中心包受累的发生率约为50%，但有症状的心包炎在约16%的弥漫性硬皮病患者和约30%的局限性硬皮病患者中出现。硬皮病中临床上明显的心包积液很少见，尽管通过超声心动图检查约41%的患者可检测到。在大多数患者中，心包积液量少且无相关症状。心包积液通常在硬皮病的其他临床和血清学特征出现之后才表现出来。本文报道了1例以大量心包积液为首发表现的硬皮病病例，该心包积液早于硬皮病的其他临床和血清学特征出现。本文对硬皮病的心包受累情况进行了综述。
