Uhl G S, Koppes G M
Br Heart J. 1979 Sep;42(3):345-8. doi: 10.1136/hrt.42.3.345.
The frequency of pericardial disease in scleroderma found at necropsy in high. The clinical recognition of pericarditis with or without effusion is rare and tamponade with haemodynamic impairment is exceptional. Three patients with scleroderma presented with an acute syndrome of dyspnoea, chest pain, and cardiomegaly requiring pericardiocentesis for relief of pericardial tamponade. One patient died. The mechanism of the pericardial effusion remains unknown. The haemodynamic data recorded from one patient suggested that pericardial fibrosis in scleroderma may predispose to pericardial tamponade.
尸检发现硬皮病中心包疾病的发生率很高。临床上对伴有或不伴有积液的心包炎的认识很少，而伴有血流动力学损害的心包填塞则极为罕见。三名硬皮病患者出现急性呼吸困难、胸痛和心脏扩大综合征，需要进行心包穿刺以缓解心包填塞。一名患者死亡。心包积液的机制尚不清楚。一名患者记录的血流动力学数据表明，硬皮病中的心包纤维化可能易导致心包填塞。
