Beausoleil J L, Spergel J M, Pawlowski N A
Division of Immunologic and Infectious Diseases, The Children's Hospital of Philadelphia, PA 19104, USA.
Ann Allergy Asthma Immunol. 2001 Jan;86(1):68-70. doi: 10.1016/S1081-1206(10)62359-9.
Potato allergy has been described rarely, generally in relation to the Oral Allergy Syndrome (OAS). Adults with seasonal allergic rhinitis have been reported in whom peeling of raw potatoes causes oculonasal symptoms, wheezing, and contact urticaria. Skin testing with fresh fruits and vegetables has been recommended in cases of OAS, although the sensitivity of commercial potato extract is reportedly equal to that of fresh potato.
This report describes a 4-year-old with raw potato-induced anaphylaxis. He rapidly developed urticaria, angioedema, respiratory distress, vomiting and diarrhea after biting into a raw potato that was being used for painting in preschool. Review of systems is significant for viral-induced wheezing, but no symptoms suggestive of seasonal allergic rhinitis were evident. His mother has a history of seasonal allergic rhinitis and contact urticaria with raw potato. Skin testing to commercial potato extract was negative and skin testing to fresh potato by the prick + prick method was markedly positive. Skin testing to birch tree was negative. An open challenge to a small amount of cooked potato was negative. Food challenge to raw potato was not considered indicated in this case of immediate anaphylaxis to a single food.
This patient had clinical and skin test reactivity to raw and uncooked potato in the absence of OAS. The patient will be followed for the development of seasonal allergic rhinitis.
马铃薯过敏很少被描述,通常与口腔过敏综合征(OAS)有关。有报道称,患有季节性过敏性鼻炎的成年人在削生土豆皮时会出现眼鼻症状、喘息和接触性荨麻疹。对于OAS病例,建议用新鲜水果和蔬菜进行皮肤试验,不过据报道,市售马铃薯提取物的敏感性与新鲜土豆相同。
本报告描述了一名4岁儿童因食用生土豆引发过敏反应。他在幼儿园咬了一口用于绘画的生土豆后,迅速出现荨麻疹、血管性水肿、呼吸窘迫、呕吐和腹泻。系统回顾显示有病毒引起的喘息,但未发现季节性过敏性鼻炎的症状。他的母亲有季节性过敏性鼻炎病史,接触生土豆会出现接触性荨麻疹。对市售马铃薯提取物进行皮肤试验呈阴性,采用点刺+点刺法对新鲜土豆进行皮肤试验呈明显阳性。对桦树进行皮肤试验呈阴性。对少量熟土豆进行开放激发试验呈阴性。对于这种对单一食物立即发生过敏反应的病例,未考虑对生土豆进行食物激发试验。
该患者在无OAS的情况下,对生土豆和未煮熟的土豆有临床和皮肤试验反应性。将对该患者进行随访,观察其是否会出现季节性过敏性鼻炎。