Muratori M, Berti M, Doria E, Antona C, Alamanni F, Sisillo E, Salvi L, Pepi M
Centro Cardiologico Fondazione I. Monzino, IRCCS, Centro di Studio per le Ricerche Cardiovascolari del CNR, Milan, Italy.
J Heart Valve Dis. 2001 Jan;10(1):65-71.
Mitral valve repair has recently emerged as the treatment of choice in patients presenting with insufficiency due to valve prolapse. The study aims were to evaluate: (i) the clinical presentation in a consecutive series of patients with mitral valve prolapse undergoing surgical repair; (ii) the correlation between pre- and intraoperative echocardiographic features and surgical findings in these patients; and (iii) whether clinical and echocardiographic data may predict surgical outcome.
Between March 1997 and May 2000, 152 patients (110 men, 42 women; mean age 59+/-13 years) were recruited into the study. All patients had myxomatous mitral valve disease causing severe regurgitation and underwent systematic examination by transesophageal echocardiography (TEE) for clear delineation of the three scallops of the posterior leaflet and juxtaposed segments of the anterior leaflet.
In 119 patients (78%) a flail valve was documented by TEE and confirmed on surgical inspection; an anterior leaflet chordal rupture was not visualized by TEE in one case. In 15 cases (10%) there was flail of the anterior leaflet, and in 105 cases (69%) flail of the posterior leaflet. A bileaflet complex prolapse without chordal rupture was found in 32 cases. On the basis of TEE evaluation, mitral valve replacement was performed electively in 10 patients (7%); the other 142 (93%) underwent mitral valve repair. Adequate repair was obtained in 93% of cases; residual mitral regurgitation (eight cases; grade 3+) and mitral stenosis (one case) were documented by intraoperative TEE, and nine patients (6%) underwent valve replacement.
The majority of patients with myxomatous mitral valve prolapse and severe regurgitation undergoing valve repair have chordal rupture of the posterior mitral leaflet, a condition in which results of valve repair are excellent. TEE provides a powerful means to define the mechanisms of mitral regurgitation and to identify the suitability of patients for valvuloplasty.
二尖瓣修复术近来已成为因瓣膜脱垂导致关闭不全患者的首选治疗方法。本研究的目的是评估:(i)连续一系列接受二尖瓣修复手术的二尖瓣脱垂患者的临床表现;(ii)这些患者术前和术中超声心动图特征与手术发现之间的相关性;以及(iii)临床和超声心动图数据是否可以预测手术结果。
在1997年3月至2000年5月期间,152例患者(110例男性,42例女性;平均年龄59±13岁)被纳入本研究。所有患者均患有黏液瘤样二尖瓣疾病导致严重反流,并接受经食管超声心动图(TEE)系统检查,以清晰描绘后叶的三个扇贝形结构和前叶相邻节段。
119例患者(78%)经TEE记录并经手术检查证实存在连枷瓣叶;1例患者经TEE未发现前叶腱索破裂。15例患者(10%)存在前叶连枷,105例患者(69%)存在后叶连枷。32例患者发现无腱索破裂的双叶复合脱垂。根据TEE评估,10例患者(7%)择期进行二尖瓣置换;其他142例患者(93%)接受二尖瓣修复。93%的病例获得了充分修复;术中TEE记录到8例患者存在残余二尖瓣反流(3+级)和1例患者存在二尖瓣狭窄,9例患者(6%)接受了瓣膜置换。
大多数患有黏液瘤样二尖瓣脱垂和严重反流并接受瓣膜修复的患者存在二尖瓣后叶腱索破裂,在这种情况下瓣膜修复效果极佳。TEE为确定二尖瓣反流机制和识别患者是否适合瓣膜成形术提供了有力手段。