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脾脓肿:6例报告及文献复习

Splenic abscess: report of six cases and review of the literature.

作者信息

Green B T

机构信息

Division of Infectious Diseases, University of South Alabama, Mobile, USA.

出版信息

Am Surg. 2001 Jan;67(1):80-5.

PMID:11206904
Abstract

Splenic abscesses are rare but appear to be increasing in frequency. Recent advances in radiologic techniques have affected the diagnosis and management. The purpose of this study was to evaluate these effects. The medical records of one institution were retrospectively reviewed and six cases of splenic abscesses seen between 1989 and 1999 were identified. All patients had predisposing conditions with metastatic hematogenous infection in three and one each with trauma, immunodeficiency, and a contiguous site of infection. Fever was present in all patients with chills and vomiting in five and three patients, respectively. Left upper quadrant tenderness appeared in four patients and leukocytosis was found in every patient except one with the acquired immunodeficiency syndrome. Chest roentgenograms were abnormal in five patients with a left pleural effusion most common. Ultrasound revealed the defect in both patients it was utilized in and computed tomography was diagnostic in all cases. The causative organisms were anaerobes in two cases and Candida albicans, Streptococcus viridans, Escherichia coli, and Citrobacter freundii each present in one case. Radiology guided percutaneous drainage was attempted in four patients but was only successful in one. Splenectomy with antibiotics was curative in the remainder with a 100 per cent survival. These data suggest that percutaneous drainage may be appropriate for certain patients initially, but the high failure rate demonstrates that splenectomy remains the standard treatment.

摘要

脾脓肿较为罕见,但发病频率似乎呈上升趋势。放射技术的最新进展已对其诊断和治疗产生影响。本研究旨在评估这些影响。对一家机构的病历进行回顾性分析,确定了1989年至1999年间所见的6例脾脓肿病例。所有患者均有易感因素,其中3例为血行性转移性感染,1例因创伤、1例因免疫缺陷、1例因临近部位感染。所有患者均有发热,分别有5例和3例伴有寒战和呕吐。4例患者出现左上腹压痛,除1例获得性免疫缺陷综合征患者外,其余患者均有白细胞增多。5例患者胸部X线片异常,最常见的是左侧胸腔积液。2例接受超声检查的患者均发现了病灶,计算机断层扫描对所有病例均有诊断价值。病原菌中,2例为厌氧菌,1例为白色念珠菌、1例为草绿色链球菌、1例为大肠杆菌、1例为弗氏柠檬酸杆菌。4例患者尝试进行放射引导下经皮引流,但仅1例成功。其余患者行脾切除术加抗生素治疗后治愈,生存率达100%。这些数据表明,经皮引流可能最初适用于某些患者,但高失败率表明脾切除术仍是标准治疗方法。

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