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重症急性胰腺炎脾动脉栓塞术后脾脓肿的管理:一项为期5年的单中心经验

Management of Splenic Abscess after Splenic Arterial Embolization in Severe Acute Pancreatitis: A 5-Year Single-Center Experience.

作者信息

Li Gang, Gao Lin, Zhou Jing, Ye Bo, Zhang Jingzhu, Qu Cheng, Ke Lu, Tong Zhihui, Li Weiqin

机构信息

Surgery Intensive Care Unit (SICU), Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.

出版信息

Gastroenterol Res Pract. 2019 Jul 1;2019:6069179. doi: 10.1155/2019/6069179. eCollection 2019.

Abstract

OBJECTIVE

To describe the management and prognosis of splenic abscess after splenic arterial embolization in severe acute pancreatitis (SAP) patients.

METHODS

This is a retrospective observational study. From August 2012 to August 2017, SAP patients with infected pancreatic necrosis (IPN) who underwent splenic arterial embolization after massive hemorrhage of the splenic artery were screened and those who developed splenic abscess were included for analysis. The demographic characteristics, etiology, treatment of splenic abscess, and clinical outcomes of these cases were collected and analyzed.

RESULTS

A total of 18 patients with splenic abscess formed after splenic arterial embolization were included for data analysis. The median age of the 18 patients was 46 years. The etiologies included biliary AP, hypertriglyceridemic AP (HTG-AP), and other causes. Ten patients underwent minimally invasive percutaneous drainage only for splenic abscess while the other eight patients received splenectomy. One patient died due to uncontrolled infection and another patient died due to massive bleeding, and the remaining sixteen patients survived.

CONCLUSION

The incidence of splenic abscess was high in patients requiring splenic arterial embolization due to massive bleeding. Our data showed that most splenic abscess could be successfully managed with minimally invasive interventions, and traditional splenectomy should serve as a backup treatment.

摘要

目的

描述重症急性胰腺炎(SAP)患者脾动脉栓塞术后脾脓肿的管理及预后。

方法

这是一项回顾性观察研究。筛选2012年8月至2017年8月期间因脾动脉大出血接受脾动脉栓塞术的感染性胰腺坏死(IPN)的SAP患者,纳入发生脾脓肿的患者进行分析。收集并分析这些病例的人口统计学特征、病因、脾脓肿的治疗方法及临床结局。

结果

共纳入18例脾动脉栓塞术后形成脾脓肿的患者进行数据分析。18例患者的中位年龄为46岁。病因包括胆源性急性胰腺炎(AP)、高甘油三酯血症性急性胰腺炎(HTG-AP)及其他原因。10例患者仅接受了脾脓肿的微创经皮引流,另外8例患者接受了脾切除术。1例患者因感染控制不佳死亡,另1例患者因大出血死亡,其余16例患者存活。

结论

因大出血需要进行脾动脉栓塞术的患者中,脾脓肿的发生率较高。我们的数据表明,大多数脾脓肿可通过微创干预成功处理,传统脾切除术应作为备用治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f77/6636444/696193da4852/GRP2019-6069179.001.jpg

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