Gualandri L, Cambiaghi S, Ermacora E, Tadini G, Gianotti R, Caputo R
Centro Malattie Cutanee Ereditarie, IRCCS Ospedale Maggiore, Universita' degli Studi di Milano, Milan, Italy.
Pediatr Dermatol. 2001 Jan-Feb;18(1):17-20. doi: 10.1046/j.1525-1470.2001.018001017.x.
Smooth muscle hamartoma is a cutaneous abnormality characterized by a disorganized proliferation of normal muscle fibers of arrector pili. Usually a single congenital hypertrichotic plaque involves the trunk and the extremities. Multiple lesions have rarely been reported in the literature. We describe three members of the same family with multiple skin-colored patches on the back and legs, histologically confirmed as smooth muscle hamartomas. To our knowledge this is the first report of multiple smooth muscle hamartomas in different members of the same family and quite interestingly involving the same skin site.
平滑肌瘤性错构瘤是一种皮肤异常，其特征为立毛肌正常肌纤维的无序增殖。通常单个先天性多毛斑块累及躯干和四肢。文献中很少报道有多发性病变。我们描述了同一家庭的三名成员，他们的背部和腿部有多个肤色斑块，经组织学证实为平滑肌瘤性错构瘤。据我们所知，这是首次报道同一家庭不同成员出现多发性平滑肌瘤性错构瘤，且非常有趣的是累及相同的皮肤部位。
