Itoh S, Kondo M, Kusaka T, Isobe K, Onishi S
Department of Pediatrics, Children's Medical Center, Kagawa Medical University, Japan.
Pediatr Int. 2001 Feb;43(1):12-5. doi: 10.1046/j.1442-200x.2001.01339.x.
Controversy has existed for many years over whether infant feeding methods are related to serum bilirubin concentrations during the first few days of life. Differences in initial jaundice patterns according to the feeding method until 72 h after birth have not been elucidated hitherto. The difference may become clear in Japanese neonates because jaundice shows a much higher peak bilirubin concentration and a later peak in Japanese neonates than in Caucasian neonates.
In the present study, we investigated variations in the transcutaneous bilirubin reading (TcB) obtained within 72 h after birth among 177 breast-fed and 494 formula-fed healthy Japanese term neonates.
There was no difference between TcB in formula-fed and breast-fed infants until the first 30 h, after which time the rate of increase in TcB was lower in formula-fed infants. Among breast-fed neonates, a good linear regression between time after birth and TcB was maintained. Similarly, weight losses in breast-fed infants at 24-48 h and 48-72 h after birth were greater than those in formula-fed infants.
The jaundice pattern in Japanese neonates from 30 to 72 h after birth according to the feeding method was different from that in Caucasian neonates.
关于婴儿喂养方式是否与出生后头几天的血清胆红素浓度有关，多年来一直存在争议。迄今为止，尚未阐明出生后72小时内根据喂养方式划分的初始黄疸模式差异。在日本新生儿中这种差异可能会更明显，因为与白种人新生儿相比，日本新生儿黄疸的胆红素峰值浓度更高且峰值出现时间更晚。
在本研究中，我们调查了177名母乳喂养和494名配方奶喂养的健康日本足月儿出生后72小时内经皮胆红素读数（TcB）的变化情况。
在出生后的前30小时内，配方奶喂养婴儿和母乳喂养婴儿的TcB没有差异，此后配方奶喂养婴儿的TcB升高速率较低。在母乳喂养的新生儿中，出生时间与TcB之间保持良好的线性回归关系。同样，母乳喂养婴儿在出生后24 - 48小时和48 - 72小时的体重减轻大于配方奶喂养婴儿。
日本新生儿出生后30至72小时根据喂养方式划分的黄疸模式与白种人新生儿不同。
