Effect of the ligation of spleen neurovascular pedicle on the morphology of hemolymph splenic nodes in Wistar rats.

Macro- and microscopic structure of hemolymph splenic nodes after ligature of spleen neurovascular pedicle was evaluated in 12 Wistar rats. The results obtained were compared with the nodes of the control group. It was found that spleen neurovascular pedicle ligation without removing the organ from abdominal cavity results in the enlargement of examined nodes and a change in their color intensity. Histological examination revealed considerable increase in erythroid elements filling mainly the medullary part of the node. The spleen underwent total atrophy. Retrogressive changes, typical for single-organ nodes were not observed. Non-hemolymph mesenteric nodes did not show any macroscopic compensatory changes.