Lactic acid: New roles in a new millennium.
作者信息
Gladden L B
机构信息
Department of Health and Human Performance, Auburn University, Auburn, AL 36849-5323, USA.
出版信息
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):395-7. doi: 10.1073/pnas.98.2.395.
Abstract
摘要
相似文献
1
Lactic acid: New roles in a new millennium.乳酸：新千年的新角色。
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):395-7. doi: 10.1073/pnas.98.2.395.
2
Clarifying the equation for modeling of VO2 kinetics above the lactate threshold.
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What does glycolysis make and why is it important?糖酵解产生了什么，以及它为什么重要？
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4
Point: Muscle lactate and H⁺ production do have a 1:1 association in skeletal muscle.要点：骨骼肌中肌肉乳酸和H⁺的产生确实存在1:1的关联。
J Appl Physiol (1985). 2011 May;110(5):1487-9; discussion 1497. doi: 10.1152/japplphysiol.01506.2010. Epub 2011 Jan 6.
5
Counterpoint: Muscle lactate and H⁺ production do not have a 1:1 association in skeletal muscle.反驳观点：骨骼肌中肌肉乳酸和H⁺生成并非呈1:1关联。
J Appl Physiol (1985). 2011 May;110(5):1489-91; discussion 1498. doi: 10.1152/japplphysiol.01506.2010a.
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Rebuttal from Robergs.罗伯格斯的反驳。
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Shaking up glycolysis: Sustained, high lactate flux during aerobic rattling.撼动糖酵解：有氧颤抖期间持续的高乳酸通量。
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Rebuttal from Vinnakota and Kushmerick.维纳科塔和库什梅里克的反驳。
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Does energy demand have an additional control in ischemia or are current models of metabolic control adequate at extremes?能量需求在局部缺血中是否存在额外的调控机制，或者当前的代谢调控模型在极端情况下是否足够？
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Comments on Point:Counterpoint: Muscle lactate and H⁺ production do/do not have a 1:1 association in skeletal muscle. Lactate and acidosis yet again?关于“正方观点：反方观点：骨骼肌中肌肉乳酸与H⁺生成存在/不存在1:1关联”的评论。乳酸与酸中毒再次被提及？
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本文引用的文献
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Lactic acid in amphibian muscle.两栖动物肌肉中的乳酸
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DETECTING THE THRESHOLD OF ANAEROBIC METABOLISM IN CARDIAC PATIENTS DURING EXERCISE.检测心脏病患者运动时无氧代谢的阈值。
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Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons.酸敏感离子通道3与心脏缺血感知神经元中的酸门控电流相匹配。
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):711-6. doi: 10.1073/pnas.98.2.711. Epub 2000 Dec 19.
4
Shaking up glycolysis: Sustained, high lactate flux during aerobic rattling.撼动糖酵解：有氧颤抖期间持续的高乳酸通量。
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):723-8. doi: 10.1073/pnas.98.2.723. Epub 2000 Dec 19.
5
Role of convective O(2) delivery in determining VO(2) on-kinetics in canine muscle contracting at peak VO(2).在犬类肌肉以最大摄氧量（VO₂）峰值收缩时，对流性氧气输送在决定VO₂动力学方面的作用。
J Appl Physiol (1985). 2000 Oct;89(4):1293-301. doi: 10.1152/jappl.2000.89.4.1293.
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Intra- and extra-cellular lactate shuttles.细胞内和细胞外乳酸穿梭
Med Sci Sports Exerc. 2000 Apr;32(4):790-9. doi: 10.1097/00005768-200004000-00011.
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Muscle as a consumer of lactate.肌肉作为乳酸的消耗者。
Med Sci Sports Exerc. 2000 Apr;32(4):764-71. doi: 10.1097/00005768-200004000-00008.
8
Cardiac and skeletal muscle mitochondria have a monocarboxylate transporter MCT1.心肌和骨骼肌线粒体含有单羧酸转运蛋白MCT1。
J Appl Physiol (1985). 1999 Nov;87(5):1713-8. doi: 10.1152/jappl.1999.87.5.1713.
9
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation.质子偶联单羧酸转运体（MCT）家族：结构、功能与调控
Biochem J. 1999 Oct 15;343 Pt 2(Pt 2):281-99.
10
Role of protons in activation of cardiac sympathetic C-fibre afferents during ischaemia in cats.猫缺血期间质子在心脏交感C纤维传入神经激活中的作用。
J Physiol. 1999 Aug 1;518 ( Pt 3)(Pt 3):857-66. doi: 10.1111/j.1469-7793.1999.0857p.x.
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