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一名儿童的成人T细胞白血病病毒I型相关肉芽肿性T细胞淋巴瘤

HTLV-I-associated granulomatous T-cell lymphoma in a child.

作者信息

Lewis J M, Vasef M A, Seabury Stone M

机构信息

Department of Dermatology, University of Iowa Health Care, Iowa City, Iowa, USA.

出版信息

J Am Acad Dermatol. 2001 Mar;44(3):525-9. doi: 10.1067/mjd.2001.111349.

Abstract

Adult T-cell leukemia/lymphoma (ATLL) is a T-cell malignancy closely associated with human T-cell lymphotropic virus-1 (HTLV-I). Because of its long latency period, ATLL occurs almost exclusively in adults. We report a case of a 13-year-old boy with an 8-year history of skin eruptions. After complete evaluation, a diagnosis of HTLV-I-associated lymphoma/leukemia was made. The T-cell lymphoma exhibited a granulomatous histomorphology. There have been very few reports of ATLL presenting in childhood and none, to our knowledge, demonstrating granulomatous histology. We conclude that ATLL may rarely present as a chronic granulomatous eruption in a child.

摘要

成人T细胞白血病/淋巴瘤(ATLL)是一种与人类嗜T细胞病毒1型(HTLV-I)密切相关的T细胞恶性肿瘤。由于其潜伏期长,ATLL几乎仅发生于成人。我们报告一例13岁男孩,有8年皮肤疹病史。经过全面评估,诊断为HTLV-I相关淋巴瘤/白血病。该T细胞淋巴瘤表现为肉芽肿性组织形态学。儿童期ATLL的报道非常少,据我们所知,尚无显示肉芽肿组织学的报道。我们得出结论,ATLL在儿童中可能很少表现为慢性肉芽肿性皮疹。

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