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[肺炎衣原体与血管病理学]

[Chlamydia pneumoniae and vascular pathology].

作者信息

Maroto Vela M C

出版信息

An R Acad Nac Med (Madr). 2000;117(2):373-86; discussion 387-91.

Abstract

An updating of the microbiological and diagnostic characteristics of Chlamydia pneumoniae is carried out, and a hypothesis formulated for its probable role in the production of the atheromatous plaque. Furthermore, the immunological results obtained from patients with peripheral vascular pathology, pneumonia from C. pneumoniae, or other genital processes from C. trachomatis, and a healthy control group are included. The presence of C. pneumoniae was revealed by PCR techniques in biopsies from patients with vascular pathology in a high percentage, particularly in samples from the carotid artery (74%) or the aortic wall (83%). The true pathogenic power of Chlamydia in vascular processes in questioned.

摘要

对肺炎衣原体的微生物学和诊断特征进行了更新,并就其在动脉粥样硬化斑块形成中可能发挥的作用提出了一种假说。此外,还纳入了从患有周围血管疾病、肺炎衣原体肺炎或沙眼衣原体引起的其他生殖器疾病的患者以及健康对照组获得的免疫学结果。通过聚合酶链反应(PCR)技术在血管疾病患者的活检组织中发现肺炎衣原体的比例很高,尤其是在颈动脉(74%)或主动脉壁(83%)的样本中。衣原体在血管病变中的真正致病力仍存在疑问。

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