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[分化基因参与天蓝色链霉菌的同源重组]

[Differentiation genes are involved in homologous recombination in Streptomyces coelicolor].

作者信息

Xiao J

机构信息

Department of Biology, Beijing Normal University, Beijing 100875, China.

出版信息

Yi Chuan Xue Bao. 2000;27(12):1108-13.

Abstract

In S. coelicolor, the rapid increase of SCP2* plasmid conjugation efficiency and that of plasmid homologous recombination efficiency associates with development of aerial mycelium. Results of test of SCP2* plasmid conjugation and plasmid homologous recombination in one bld mutant and in three whi mutants show that while whiA mutant causes unstable plasmid conjugation efficiency, the other three mutants show no influence on plasmid conjugation, plasmid homologous recombination efficiency drops however more than 10 times in the four mutants.

摘要

在天蓝色链霉菌中,SCP2质粒接合效率和质粒同源重组效率的快速增加与气生菌丝体的发育相关。对一个bld突变体和三个whi突变体进行的SCP2质粒接合和质粒同源重组测试结果表明,虽然whiA突变体导致质粒接合效率不稳定,但其他三个突变体对质粒接合没有影响,不过这四个突变体中的质粒同源重组效率下降了10倍以上。

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