Karachunskiĭ M A, Kaminskiĭ G O, Kossiĭ Iu E
Probl Tuberk. 2000(6):39-41.
Intensive pulmonary tuberculosis treatment was performed in 65 patients with this disease concurrent with diabetes according to the WHO recommendations. Among them there were 44 new cases and 21 cases with relapse. Comparing the hepatic functional parameters before the first intensive stage of treatment and after its termination (following 2-3 months) showed a regular and statistically significant increase in the activity of aminotransferases and a clear tendency for increases in the values of total bilirubin and thymol tests. These changes were equally pronounced with both treatment regimens in patients with types both I and II diabetes mellitus and within normal ranges and allowed the drug treatment regimens to be continued.
根据世界卫生组织的建议,对65例并发糖尿病的重症肺结核患者进行了强化治疗。其中有44例新发病例和21例复发病例。比较治疗第一个强化阶段开始前和结束后(2 - 3个月后)的肝功能参数,发现转氨酶活性有规律且在统计学上有显著升高,总胆红素和麝香草酚浊度试验值有明显升高趋势。在I型和II型糖尿病患者中,两种治疗方案下这些变化均同样明显且在正常范围内,药物治疗方案得以继续。