Sato Y, Ochiai H, Yamakawa Y, Nabeshima K, Asada Y, Hayashi T
Department of Pathology, Prefectural Hospital Miyazaki, Miyazaki Medical College, Japan.
Neuropathology. 2000 Dec;20(4):315-8. doi: 10.1046/j.1440-1789.2000.00355.x.
A case of brain surface ependymoma is reported here. A 41-year-old woman presented with weakness of the right upper limb. Magnetic resonance imaging revealed a left fronto-parietal cystic tumor with a calcified mural nodule. Total removal of the tumor was performed. This tumor was located within the surface portion of the fronto-parietal parenchyma and was sharply demarcated from the surrounding brain tissue, and there was no continuity with the ventricles. Histological examination of this tumor showed monotonous proliferation of tumor cells with moderate cellularity and occasional mitoses, forming true ependymal rosettes and perivascular pseudorosettes with fibrillary background. A clear cell component resembling oligodendroglioma was partly noted. The tumor cells showed positive immunoreaction for glial fibrillary acid protein and vimentin.
本文报告一例脑表面室管膜瘤。一名41岁女性因右上肢无力就诊。磁共振成像显示左额顶叶囊性肿瘤,伴有钙化壁结节。肿瘤被完整切除。该肿瘤位于额顶叶实质的表面部分,与周围脑组织界限清晰,与脑室无连续性。肿瘤组织学检查显示肿瘤细胞呈单一性增殖,细胞密度中等,偶见核分裂,形成真性室管膜菊形团和血管周围假菊形团,背景为纤维状。部分区域可见类似少突胶质细胞瘤的透明细胞成分。肿瘤细胞对胶质纤维酸性蛋白和波形蛋白呈阳性免疫反应。