Zhang Ji, Sai Ke, Wang Jian, Chen Yin Shen, Yan Shu-Mei, Chen Zhong-Ping
Department of Neurosurgery, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, PR China.
State Key Laboratory of Oncology in South China and Department of Pathology, Sun Yat-sen University Cancer Center Guangzhou, PR China.
Clin Neurol Neurosurg. 2014 Sep;124:142-5. doi: 10.1016/j.clineuro.2014.06.016. Epub 2014 Jul 2.
Ependymona occasionally occurs outside the ventricular structures, which is called ectopic ependymona (EE), while pure cortex location is uncommon. However, cortical anaplastic ependymoma (CE) is rare, especially in children. There were only four primary CEs, which is located in the superficial cortex, were reported the age of the patient under 12 years old. The present case is a 20-month-old boy presenting with simple partial seizure was treated in our department. Cranial magnetic resonance imaging (MRI) revealed a fronto-parietal lobe mass of more than 50mm in diameter with mixed signal intensity. Total removal of the mass lesion was performed without any neurological deficit. Pathological examination of the excised tumor were consistent with anaplastic ependymoma (AE). The patient had a good recovery after his surgical resection. Radiotherapy and chemotherapy were not taken into account in view of his age, the favorable site and the complete resection. The management of this unusual tumor is summarized in this paper.
室管膜瘤偶尔会出现在脑室结构之外，这被称为异位室管膜瘤（EE），而单纯位于皮质的情况并不常见。然而，皮质间变性室管膜瘤（CE）很罕见，尤其是在儿童中。仅有4例原发性CE被报道，其位于浅表皮质，患者年龄在12岁以下。本病例为一名20个月大的男孩，因单纯部分性发作在我科接受治疗。头颅磁共振成像（MRI）显示额顶叶有一个直径超过50mm的肿块，信号强度混杂。完整切除了肿块病变，未出现任何神经功能缺损。切除肿瘤的病理检查结果与间变性室管膜瘤（AE）一致。患者手术切除后恢复良好。鉴于其年龄、肿瘤位置良好且完整切除，未考虑进行放疗和化疗。本文总结了这种罕见肿瘤的治疗方法。
