Takahashi N, Tsunematsu K, Sugawara H, Kusajima K, Abe T
Department of Thoracic Surgery, Hokkaido Tomakomai Hospital, Tomakomai, Japan.
Kyobu Geka. 2001 Feb;54(2):141-5.
We had reported on the basis of experimental findings that the efficacy of protecting the suture line in tracheoplasty by using a self-fascia lata and GRF glue. This time we investigated the effectiveness of GRF glue in the respiratory surgery on the basis of clinical findings. All ten cases in which GRF glue was used resulted in an excellent outcome, namely, GRF glue prevented from air leakage, bleeding and leakage of chyle. Moreover, it was not recognized that any grave side effects occurred in any cases after using GRF glue. We could conclude that GRF glue was a useful material for the respiratory surgery, especially for the case that had a dead space after lobectomy. However its price is not inexpensive, therefore, there seems need to restrict the use of GRF glue--for example--to cases of Giant bulla resection, residual of a large dead space as a postoperative possibility and chemotherapy performed before an operation, and so on.
我们曾根据实验结果报道过，使用自体阔筋膜和GRF胶水在气管成形术中保护缝线的效果。此次我们根据临床结果研究了GRF胶水在呼吸外科手术中的有效性。使用GRF胶水的所有10例病例均取得了极佳的效果，即GRF胶水防止了漏气、出血和乳糜漏。此外，在使用GRF胶水后，未发现任何病例出现严重的副作用。我们可以得出结论，GRF胶水是呼吸外科手术中的一种有用材料，特别是对于肺叶切除术后有死腔的病例。然而，其价格并不便宜，因此，似乎有必要限制GRF胶水的使用——例如——仅限于巨大肺大泡切除、术后可能残留大死腔以及术前进行化疗等病例。
