Takahashi N, Ichimiya Y, Mawatari T, Kusajima K, Komatsu S
Second Department of Surgery, Sapporo Medical University School of Medicine, Hokkaido, Japan.
Surg Today. 1997;27(11):1046-50. doi: 10.1007/BF02385786.
We examined the efficacy of protecting the suture line in tracheoplasty by using a self-fascia lata and Gelatin-Resorcin-Formal (GRF) glue. Fifteen dogs underwent a resection of four rings of the trachea and reconstruction, and we then observed them for one month; group A (n = 5) without reinforcement, group B (n = 5) with a self-fascia-lata spread with GRF glue, and group C (n = 5) with only a self-fascia-lata. In the reinforced dogs (group B, three cases, and group C, five cases), in which the continuity of the suture line had been conserved, eight cases were resistant to pressures of from 240 mmHg to 300 mmHg, and two cases (both in group B) which had a partial discontinuity of the suture line were resistant to the same pressure of 160 mmHg. But in the five dogs without reinforcement (group A), four died from infection due to leakage of the trachea within 2 weeks; only one that had a continuity of the suture line survived and was resistant to pressure of 300 mmHg. These results show that a reinforcement of tracheoplasty using a self-fascia lata and GRF glue is useful for preventing air leakage from the suture line.
我们研究了使用自体阔筋膜和明胶-间苯二酚-甲醛（GRF）胶水保护气管成形术缝线的效果。15只狗接受了气管四环切除及重建手术，然后对它们进行了为期一个月的观察；A组（n = 5）未进行加固，B组（n = 5）使用涂抹了GRF胶水的自体阔筋膜进行加固，C组（n = 5）仅使用自体阔筋膜进行加固。在缝线连续性得以保留的加固组狗中（B组3例，C组5例），8例能够耐受240 mmHg至300 mmHg的压力，而缝线有部分间断的2例（均在B组）能够耐受160 mmHg的相同压力。但在未进行加固的5只狗（A组）中，4只在2周内死于气管渗漏引起的感染；只有1只缝线保持连续的狗存活下来，并且能够耐受300 mmHg的压力。这些结果表明，使用自体阔筋膜和GRF胶水对气管成形术进行加固有助于防止缝线处漏气。
