Zhou S, Cook K D
Department of Chemistry, University of Tennessee, Knoxville 37996-1600, USA.
J Am Soc Mass Spectrom. 2001 Feb;12(2):206-14. doi: 10.1016/S1044-0305(00)00213-0.
A model has been developed to account qualitatively for the effects of ion pairing, surface activity, and electrophoretic mobility in electrospray mass spectrometry. The model is tested with various salt and amino acid mixtures. The data suggest that the axial charge gradient arising from electrophoretic separation at droplet genesis may persist within the electrosprayed droplets at least until the first droplet fission, accounting for the field dependence of detected ion clustering of quaternary ammonium salts and for the relatively field-invariant charge distribution of horse heart myoglobin samples.
已开发出一个模型，用于定性解释电喷雾质谱中离子配对、表面活性和电泳迁移率的影响。该模型用各种盐和氨基酸混合物进行了测试。数据表明，在液滴形成时由电泳分离产生的轴向电荷梯度可能至少在电喷雾液滴内持续到第一次液滴分裂，这解释了季铵盐检测到的离子簇的场依赖性以及马心肌红蛋白样品相对场不变的电荷分布。
