酒精依赖对人体十二指肠双糖酶水平的影响。
Effect of alcohol dependence on the levels of duodenal disaccharidases in human subjects.
作者信息
Lhatoo S D, Bhasin D K, Rana S V, Katyal R, Singh K
机构信息
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012.
出版信息
Indian J Physiol Pharmacol. 2000 Oct;44(4):495-9.
BACKGROUND
The aim of the study was to detect the duodenal enzyme activity in patients of alcohol dependence and to compare with non-alcoholic patients of non-ulcer dyspepsia.
METHODS
Disaccharidases (lactase, sucrase, maltase) were estimated in 20 non alcoholic patients of non-ulcer dyspepsia and 20 alcoholics admitted to the drug de-addiction and treatment centre of PGIMER, Chandigarh, India.
RESULTS
No significant influence of alcohol on enzyme levels in patients of alcohol dependence when compared to patients of non-ulcer dyspepsia was observed. However, a significant decrease in lactase level was noted in patients consuming more than 125 gm/day of alcohol.
CONCLUSION
Amount of consumption of alcohol showed decrease in lactase enzyme, but not in maltase and sucrase. There was no effect of duration of alcohol consumption on dissacharidases in the two groups.
背景
本研究的目的是检测酒精依赖患者的十二指肠酶活性，并与非溃疡性消化不良的非酒精性患者进行比较。
方法
在印度昌迪加尔PGIMER戒毒和治疗中心收治的20例非溃疡性消化不良的非酒精性患者和20例酒精依赖患者中，对双糖酶（乳糖酶、蔗糖酶、麦芽糖酶）进行了评估。
结果
与非溃疡性消化不良患者相比，未观察到酒精对酒精依赖患者酶水平有显著影响。然而，每天饮酒超过125克的患者乳糖酶水平显著降低。
结论
酒精摄入量显示乳糖酶减少，但麦芽糖酶和蔗糖酶未减少。两组中饮酒持续时间对双糖酶没有影响。
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