Al-Qarawi A A, Mahmoud O M, Haroun E M, Adam S E
Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, King Saud University, Saudi Arabia.
Vet Res Commun. 2001 Jan;25(1):61-70. doi: 10.1023/a:1026762002947.
The anthelmintic activity of Calotropis procera latex was investigated in sheep that had been infected with single oral doses of 12000 infective Haemonchus contortus larvae. Inappetence, dullness, erosive abomasitis, decreased haemoglobin concentration and increased eosinophils were the main features of haemonchosis in the sheep. In the sheep treated with single oral doses of 0.01 ml or 0.02 ml/kg body weight of C. procera latex, egg production was significantly reduced, but not completely suppressed, and fewer adult Haemonchus worms were found in the abomasum. Although the appetite improved, the haemoglobin concentration and serum copper, iron and zinc levels were still reduced after therapy with Calotropis latex. Calotropis latex showed a concentration-dependent larvicidal activity in vitro within 20 min of application.
在口服单剂量12000条感染性捻转血矛线虫幼虫的绵羊中，研究了牛角瓜乳汁的驱虫活性。食欲不振、精神沉郁、糜烂性皱胃炎、血红蛋白浓度降低和嗜酸性粒细胞增多是绵羊血矛线虫病的主要特征。在口服单剂量0.01 ml或0.02 ml/kg体重牛角瓜乳汁治疗的绵羊中，产卵量显著减少，但未完全抑制，且在皱胃中发现的成年血矛线虫较少。虽然食欲有所改善，但用牛角瓜乳汁治疗后，血红蛋白浓度以及血清铜、铁和锌水平仍降低。在体外应用后20分钟内，牛角瓜乳汁表现出浓度依赖性杀幼虫活性。
