Kataoka H, Furuya Y, Chuma T, Suzumura A
Department of Neurology, Hirai Hospital.
No To Shinkei. 2000 Nov;52(11):1013-7.
In cranial pachymeningitis, headache, cranial nerve palsies, and ataxia were the most common clinical manifestations. We reported two rare cases presenting only headache or convulsion as a main symptom. A 66-year-old man was suffering from severe continuous headache for years with no other clinical symptoms. Laboratory data revealed positive RA test and elevated RAPA. With oral steroid therapy, his headache was subsided. A 39-year-old woman visited us with convulsive attacks as only symptom. Biopsy of the thickened dura revealed granulated epithelioid cells without central necrosis. With antituberculosis therapy, hypertrophy of dura, as well as the symptom, was disappeared. It is difficult to diagnose pachymeningitis when patients manifest only headache or convulsion. We suggest to carry out Gd-enhanced MR scan in these cases.
在颅骨硬脑膜炎中,头痛、颅神经麻痹和共济失调是最常见的临床表现。我们报告了两例罕见病例,仅以头痛或惊厥为主要症状。一名66岁男性多年来一直遭受严重的持续性头痛,无其他临床症状。实验室数据显示类风湿因子(RA)检测呈阳性,类风湿关节炎相关肽(RAPA)升高。经口服类固醇治疗后,他的头痛缓解。一名39岁女性仅以惊厥发作为唯一症状前来就诊。增厚硬脑膜的活检显示有颗粒状上皮样细胞,无中央坏死。经抗结核治疗后,硬脑膜增厚以及症状均消失。当患者仅表现为头痛或惊厥时,很难诊断为硬脑膜炎。我们建议在这些病例中进行钆增强磁共振扫描。