Doede T, Foss H D, Waldschmidt J
Department of Pediatric Surgery, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Germany.
Eur J Pediatr Surg. 2000 Dec;10(6):372-7. doi: 10.1055/s-2008-1072394.
Incidental detection of a carcinoid tumor of the appendix after appendectomy is often accompanied by uncertainty about the further procedure. The tumor frequency in our own patient population, the further course in these children and a practicable follow-up protocol have to be determined.
All appendectomies performed between January 1, 1982, and December 31, 1996, were retrospectively evaluated with regard to carcinoids, monitoring the clinical course, and follow-up of the patients involved.
A total of 4747 appendectomies were performed, 8 children had a histologically manifest carcinoid (0.169%). All patients were symptom-free in the further course, no metastases or signs of a carcinoid were documented during a mean follow-up period of 6.6 years.
The youngest patient with a metastasizing carcinoid tumor of the appendix reported in the literature was 19 years old. Nevertheless, all younger patients should undergo regular follow-ups; this is done in our department by serum serotonin and chromogranin A determination.
阑尾切除术后偶然发现阑尾类癌肿瘤，后续治疗方案往往难以确定。我们需要确定自身患者群体中的肿瘤发生率、这些儿童的后续病程以及切实可行的随访方案。
对1982年1月1日至1996年12月31日期间进行的所有阑尾切除术进行回顾性评估，检查类癌情况，监测临床病程，并对相关患者进行随访。
共进行了4747例阑尾切除术，8名儿童组织学上确诊为类癌（0.169%）。所有患者在后续病程中均无症状，平均随访6.6年期间未记录到转移或类癌迹象。
文献报道中最年轻的阑尾类癌转移患者为19岁。然而，所有较年轻患者均应定期随访；我们科室通过测定血清5-羟色胺和嗜铬粒蛋白A进行随访。
