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阑尾类癌肿瘤——过去十年的经验

Carcinoid tumors of the appendix - last decade experience.

作者信息

Anastasiadis Kleanthis, Kepertis Chrysostomos, Lampropoulos Vasilios, Tsioulas Paschalis, Spyridakis Ioannis

机构信息

Resident in Pediatric Surgery, 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece .

Pediatric Surgeon, 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece .

出版信息

J Clin Diagn Res. 2014 Nov;8(11):NC01-2. doi: 10.7860/JCDR/2014/10694.5151. Epub 2014 Nov 20.

Abstract

INTRODUCTION

Carcinoid of the appendix is a rare clinical entity in childhood and usually has a good clinical outcome. The impact of the operative preparations appendix ranges between 0.1-0.9%. The aim of our study is to report the experiences of our department in the management of appendiceal carcinoid tumors in children.

MATERIALS AND METHODS

Data of all patients aged 15 y or less who underwent appendectomy at the 2nd Department of Pediatric Surgery of Aristotle University of Thessaloniki between January 2004 and February 2014 were evaluated for the existence of appendiceal carcinoid tumors in pathological specimens. The collected data included: gender, patient's age, clinical indications and surgical intervention, tumor localization in the appendix and the diameter of lesion, histological type of the tumor and postoperative care (follow up) of patients.

RESULTS

Four cases (3 girls, 1 boy) with carcinoid treated at our department during a 10 y period. Median patient age was 10.75 y (9- 12 y). In all cases the diagnosis was after appendectomy on ground of acute appendicitis. A single incident brought findings of gangrenous appendicitis. In three cases the tumor's diameter was smaller than 1cm, while the incident with the gangrenous appendicitis was larger than 1cm in diameter. In four cases the tumor was localized at the apex of the appendix without extending to the surrounding tissues. In all patients with carcinoid tumor followed a further testing based on specific monitoring protocol. In no case was residual or metastatic disease identified and no further treatment was required. No relapse was observed during follow-up.

CONCLUSION

Our study confirms the good prognosis of appendiceal carcinoid.

摘要

引言

阑尾类癌在儿童期是一种罕见的临床病症,通常临床预后良好。阑尾类癌的手术发病率在0.1%至0.9%之间。我们研究的目的是报告我们科室在儿童阑尾类癌肿瘤管理方面的经验。

材料与方法

对2004年1月至2014年2月在塞萨洛尼基亚里士多德大学第二小儿外科接受阑尾切除术的所有15岁及以下患者的数据进行评估,以确定病理标本中是否存在阑尾类癌肿瘤。收集的数据包括:性别、患者年龄、临床指征和手术干预、肿瘤在阑尾中的定位及病变直径、肿瘤的组织学类型以及患者的术后护理(随访)。

结果

在10年期间,我们科室共治疗了4例类癌患者(3名女孩,1名男孩)。患者中位年龄为10.75岁(9至12岁)。所有病例均在因急性阑尾炎行阑尾切除术后确诊。有1例出现坏疽性阑尾炎。3例肿瘤直径小于1厘米,而坏疽性阑尾炎病例的肿瘤直径大于1厘米。4例肿瘤均位于阑尾尖端,未累及周围组织。所有类癌肿瘤患者均按照特定监测方案进行了进一步检查。未发现残留或转移性疾病,无需进一步治疗。随访期间未观察到复发。

结论

我们的研究证实了阑尾类癌的良好预后。

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