Schurig V
Institute of Organic Chemistry, University of Tübingen, Germany.
J Chromatogr A. 2001 Jan 12;906(1-2):275-99. doi: 10.1016/s0021-9673(00)00505-7.
The separation of enantiomers by gas chromatography is performed on chiral stationary phases (CSPs) via hydrogen bonding, coordination and inclusion. Thus, typical chiral selectors are amino acid derivatives, terpene-derived metal coordination compounds and modified cyclodextrins. In Chirasil-type stationary phases the chiral selector is anchored to a polysiloxane backbone improving gas chromatographic performance. The present review article describes the state-of-the-art, scope and limitations, applications and mechanistic considerations at the advent of the millennium incorporating 16 figures and 168 references.
对映体的气相色谱分离是在手性固定相（CSPs）上通过氢键、配位和包合作用来实现的。因此，典型的手性选择剂是氨基酸衍生物、萜烯衍生的金属配位化合物和改性环糊精。在Chirasil型固定相中，手性选择剂锚定在聚硅氧烷主链上，从而提高了气相色谱性能。本文综述描述了千年之交时的技术现状、范围和局限性、应用以及机理方面的考虑，包含16幅图和168篇参考文献。
