Enantioseparations in super- and subcritical fluid chromatography.

The separation of chiral compounds by sub- and supercritical fluid chromatography has been a field of great progress since the first demonstration of a chiral separation by SFC in 1985. Almost all of the chiral selectors used in gas or liquid chromatography have been successfully applied to sub-/supercritical chromatography. Easier and faster method development, high efficiency, superior and rapid separations of a wide variety of analytes, extended-temperature capability, analytical and preparative-scale equipment improvements and a selection of detection options have been reported.