Engeler V, Stadelmann R, Menges V
Schweiz Med Wochenschr. 1975 Jan 18;105(3):87-90.
As a rule the diagnosis of larger focal lesions of the breast can be easily confirmed by biopsy. Intraoperative localization is more difficult, however, in lesions of below 5 mm diameter as measured by mammography or malignant alterations only indirectly indicated by mammography. Experience to date in 64 patients shows that specimen radiography provides immediate confirmation of large lesions detected by mammography and localizes the area for histologic examination. So far it has been found that precisely those biopsies that are performed as a result of indirect signs of malignancy or of small lesions are the most valuable contributing factor in the early diagnosis of breast cancer.
通常,乳腺较大局灶性病变的诊断可通过活检轻易确诊。然而,对于乳腺钼靶测量直径小于5mm的病变或仅由乳腺钼靶间接提示的恶性病变,术中定位则更为困难。迄今为止,对64例患者的经验表明,标本射线摄影可立即证实乳腺钼靶检测到的大病变,并确定组织学检查的区域。到目前为止,已经发现恰恰是那些因恶性间接征象或小病变而进行的活检,是乳腺癌早期诊断中最有价值的因素。