Nakayama Y, Sakata R, Ura M
Department of Cardiovascular Surgery, Kumamoto Central Hospital, Japan.
Ann Thorac Surg. 2001 Jan;71(1):142-7. doi: 10.1016/s0003-4975(00)02178-0.
The growth potential of the internal thoracic artery (ITA) is still undetermined, and little is known about the long-term effects of anastomosing it to the coronary artery.
Fifty-three patients whose left ITA (LITA) had been anastomosed to the left anterior descending (LAD) coronary artery underwent coronary angiography within 1 month of operation and in late follow-up (mean interval: 4.5 +/- 1.5 years). The diameter ratios of LITA to LAD were designated as the matching ratio.
In follow-up, the diameter of the LITA increased from 1.83 +/- 0.40 to 2.46 +/- 0.53 mm in the 29 patients with progressive proximal native coronary stenosis. However, late results indicate that the matching ratio did not vary according to the location of the LITA anastomosis on the LAD (proximal portion: 1.13 +/- 0.16, distal portion 1.19 +/- 0.13), and reached an upper limit of about 1.4.
Growth potential of the LITA is limited by the diameter of the coronary artery onto which it is anastomosed. The most effective procedure for enhancing the growth potential of the LITA is to anastomose as proximally as possible onto the LAD.
胸廓内动脉（ITA）的生长潜力仍未确定，关于将其与冠状动脉吻合的长期影响知之甚少。
53例左胸廓内动脉（LITA）已与左前降支（LAD）冠状动脉吻合的患者在术后1个月内及晚期随访（平均间隔时间：4.5±1.5年）时接受了冠状动脉造影。LITA与LAD的直径比被指定为匹配比。
在随访中，29例近端原位冠状动脉进行性狭窄患者的LITA直径从1.83±0.40 mm增加到2.46±0.53 mm。然而，晚期结果表明，匹配比并不根据LITA在LAD上的吻合位置而变化（近端部分：1.13±0.16，远端部分1.19±0.13），并且达到约1.4的上限。
LITA的生长潜力受到其吻合的冠状动脉直径的限制。增强LITA生长潜力的最有效方法是尽可能在近端与LAD吻合。
