Barner Hendrick B
Washington University School of Medicine, St. Louis, Missouri, USA.
Jpn J Thorac Cardiovasc Surg. 2002 Dec;50(12):541-53. doi: 10.1007/BF02913172.
The first three decades of coronary artery surgery have provided the foundation for the next century of this evolution. It is apparent that a multitude of events including the development of cardioplegia, improving surgical instrumentation, technological advances including endoscopic approaches and computer assisted robotics and biologic discoveries such as the role of the endothelium have provided the underpinnings for improved surgical outcomes. However, the single most important determinant of late results is the type of bypass conduit used for grafting. Thus, use of the left internal thoracic artery (ITA) grafted to the left anterior descending coronary is a more important determinant of survival than is any other factor (progression of coronary artery disease, increased age, poor left ventricular function, diabetes, female gender and off-pump operations). Use of two ITAs provides further benefit and it is likely that three or more arterial conduits will be shown to be advantageous in this regard in due time. Japanese cardiothoracic surgeons have made significant contributions to the continuing evolution of coronary bypass surgery and particularly to the advance of arterial conduits. This report will address those contributions to this evolution.
冠状动脉手术的头三十年为该领域下个世纪的发展奠定了基础。显然,包括心脏停搏液的发展、手术器械的改进、包括内镜手术方法和计算机辅助机器人技术在内的技术进步以及诸如内皮作用等生物学发现等众多事件,为手术效果的改善提供了支撑。然而,远期结果的最重要单一决定因素是用于移植的旁路血管类型。因此,将左胸廓内动脉(ITA)移植到左前降支冠状动脉比任何其他因素(冠状动脉疾病进展、年龄增长、左心室功能差、糖尿病、女性性别和非体外循环手术)对生存的影响更为重要。使用两支ITA可带来更多益处,并且很可能在适当的时候会证明三支或更多动脉血管在这方面具有优势。日本心胸外科医生对冠状动脉搭桥手术的持续发展,尤其是对动脉血管的发展做出了重大贡献。本报告将阐述他们在这一发展过程中的贡献。