Jendrossek D
Institut für Mikrobiologie der Universität Stuttgart, Allmandring 31, 70569 Stuttgart, Germany.
Adv Biochem Eng Biotechnol. 2001;71:293-325. doi: 10.1007/3-540-40021-4_10.
Polyesters, such as microbially produced poly[(R)-3-hydroxybutyric acid] [poly(3HB)], other poly[(R)-hydroxyalkanoic acids] [poly(HA)] and related biosynthetic or chemosynthetic polyesters are a class of polymers that have potential applications as thermoplastic elastomers. In contrast to poly(ethylene) and similar polymers with saturated, non-functionalized carbon backbones, poly(HA) can be biodegraded to water, methane, and/or carbon dioxide. This review provides an overview of the microbiology, biochemistry and molecular biology of poly(HA) biodegradation. In particular, the properties of extracellular and intracellular poly(HA) hydrolyzing enzymes [poly(HA) depolymerases] are described.
聚酯，如微生物产生的聚[(R)-3-羟基丁酸] [聚(3HB)]、其他聚[(R)-羟基链烷酸] [聚(HA)]以及相关的生物合成或化学合成聚酯，是一类具有作为热塑性弹性体潜在应用的聚合物。与具有饱和、非官能化碳主链的聚乙烯及类似聚合物不同，聚(HA)可被生物降解为水、甲烷和/或二氧化碳。本综述概述了聚(HA)生物降解的微生物学、生物化学和分子生物学。特别描述了细胞外和细胞内聚(HA)水解酶[聚(HA)解聚酶]的特性。
